Recombinant Anti-human G3BP1 Intrabody [Tat] (CAT#: IAB-B011(T))
Recombinant anti-G3BP1 intrabody in fusion with HIV Tat works within cells and specifically reacts with human G3BP1, expressed in 293T cells.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- human GTPase activating protein (SH3 domain) binding protein 1
- Host Species
- human
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- human
- Applications
- Products can be used for: Western blot; Immunocytochemistry; Neutralization; Functional studies
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- G3BP1; GTPase activating protein (SH3 domain) binding protein 1; G3BP; HDH-VIII; ras GTPase-activating protein-binding protein 1; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP SH3 domain-binding protein 1; RasGAP-associated endoribonuc
- Gene ID
- 10146
- UniProt ID
- Q13283
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-381 | Recombinant Anti-human G3BP1 Antibody | WB, IP, FuncS | IgG |
| MHH-381 | Recombinant Human Anti-human G3BP1 Antibody | ELISA, WB, FuncS | IgG |
| MOB-2425MZ | Recombinant Mouse Anti-Human G3BP1 Antibody | FC, ICC/IF, IHC-P, WB | Mouse antibody |
| VS3-FY571 | Recombinant Rabbit Anti-G3BP1 Antibody (clone R06-5D2) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
| VS3-FY572 | Recombinant Rabbit Anti-G3BP1 Antibody (clone R09-5B9) | WB, ICC, IF, IP | Rabbit IgG |
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