This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-GD2 IgG to IL12 and IL2. It was expressed in CHO and purified with affinity chromatography. The Immunocytokines retains the ability to bind the GD2 as well as the biological activity of IL12 and IL2. The fusion proteins comprise a heterodimeric form of IL-12 in which the p35 and p40 subunits of IL-12 are linked by a disulfide bond and covalently bonded to a secondcytokine at either the amino or carboxyl terminus of the p35 or p40 subunit of IL-12. This Immunocytokines was designed for treating neuroblastomas, medulloblastomas, astrocytomas, melanomas, small-cell lung cancer, osteosarcomas and other soft tissue sarcomas. .
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-770-sdAb | Recombinant Anti-Human GD2 VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-731 | Anti-GD2 Recombinant Antibody (Dinutuximab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L018R | anti-GD2 immunotoxin 14G2a (IgG)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-304CL | Anti-Human GD2 Recombinant Antibody (hu14.18K322A) | FC, FuncS | Antibody |
PABX-059 | Human Anti-GD2 Recombinant Antibody (PABX-059) | FuncS | IgG1, κ |
PABX-059-F (E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E)) | FC, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-100 | Mouse Anti-GD2 Recombinant Antibody (clone 14G2a) | ELISA, WB, FuncS | Mouse IgG |
PABL-101 | Mouse Anti-GD2 Recombinant Antibody (clone 3F8) | FC, ELISA, FuncS | Mouse IgG |
FAMAB-0126YC | Mouse Anti-GD2 Recombinant Antibody (clone 7A4) | ELISA | Mouse IgG3, κ |
HPAB-0027-WJ | Mouse Anti-GD2 Recombinant Antibody (HPAB-0027-WJ) | ELISA, RIA | Mouse IgG3, κ |
HPAB-1030WJ | Human Anti-GD2 Recombinant Antibody (HPAB-1030WJ) | ELISA | Chimeric (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-100 | Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
PSBL-101 | Mouse Anti-GD2 Recombinant Antibody (clone 3F8); scFv Fragment | FC, ELISA, FuncS | Mouse scFv |
MOB-181CQ | Human Anti-GD2 Recombinant Antibody (MOB-181CQ) | ELISA, FC, FuncS | Humanized scFv |
FAMAB-0126-YC-S(P) | Mouse Anti-GD2 Recombinant Antibody (clone 7A4); scFv Fragment | ELISA | Mouse scFv |
HPAB-1030WJ-S(P) | Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-1030WJ-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-100 | Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
PFBL-101 | Mouse Anti-GD2 Recombinant Antibody (clone 3F8); Fab Fragment | FC, ELISA, FuncS | Mouse Fab |
HPAB-0027-WJ-F(E) | Mouse Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-0027-WJ-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1030WJ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-1030WJ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
HPAB-1524WJ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM8138) | ELISA, WB | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-074CQ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-074CQ-F(E)) | ELISA, FC | Human Fab |
TAB-075CQ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-075CQ-F(E)) | ELISA, FC | Human Fab |
TAB-076CQ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-076CQ-F(E)) | ELISA, FC | Human Fab |
TAB-077CQ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-077CQ-F(E)) | ELISA, FC | Human Fab |
TAB-078CQ-F(E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-078CQ-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-029CN | Mouse Anti-GD2 Recombinant Antibody (clone 5F11) | WB | Mouse IgG |
NS-030CN | Mouse Anti-GD2 Recombinant Antibody (clone 3G6) | WB | Mouse IgG |
NS-029CN-F(E) | Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment | WB | Mouse Fab |
NS-030CN-F(E) | Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment | WB | Mouse Fab |
NS-029CN-S(P) | Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment | WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-731 | Afuco™ Anti-GD2 ADCC Recombinant Antibody (Dinutuximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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