Mouse Anti-GDF11 Recombinant Antibody (clone CBL644) (CAT#: NEUT-859CQ)
This antibody is a mouse monoclonal antibody that binds specifically to GDF-11/GDF-8, and it can neutralize the bioactivity of GDF-11/GDF-8.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
Figure 3 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
Figure 4 Cerebral cortex
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
Figure 5 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11
Specifications
- Immunogen
- Recombinant human GDF-11/BMP-11 Asn299-Ser407
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human GDF11
- Species Reactivity
- Human
- Clone
- CBL644
- Applications
- Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- GDF11; growth differentiation factor 11; BMP11; BMP-11
- Gene ID
- 10220
- UniProt ID
- O95390
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-390 | Recombinant Anti-human GDF11 Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-390 | Recombinant Human Anti-human GDF11 Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0265CT | Recombinant Mouse anti-Human GDF11 Monoclonal antibody (EML1029) | IHC-P | |
| MRO-1696-CN | Rabbit Anti-GDF11 Polyclonal Antibody (MRO-1696-CN) | IF, IHC, FC | Rabbit IgG |
| VS3-FY2115 | Rabbit Anti-GDF11 Recombinant Antibody (clone R41-2N-8) | WB, IHC-P, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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