Mouse Anti-GDF11 Recombinant Antibody (clone CBL644) (CAT#: NEUT-859CQ)
This antibody is a mouse monoclonal antibody that binds specifically to GDF-11/GDF-8, and it can neutralize the bioactivity of GDF-11/GDF-8.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1118_F9_3_selected.jpg
Figure 3 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60985/1261_D2_3_blue_red_green.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in a subset of glial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_7_5_selected.jpg
Figure 4 Cerebral cortex
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
(Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_B_9_5.jpg
Figure 5 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69609/161896_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135414-GDF11
Specifications
- Immunogen
- Recombinant human GDF-11/BMP-11 Asn299-Ser407
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human GDF11
- Species Reactivity
- Human
- Clone
- CBL644
- Applications
- Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- GDF11; growth differentiation factor 11; BMP11; BMP-11
- Gene ID
- 10220
- UniProt ID
- O95390
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Fab Antibodies
ScFv Antibodies
Rabbit Monoclonal Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-390 | Recombinant Anti-human GDF11 Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-390 | Recombinant Human Anti-human GDF11 Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0265CT | Recombinant Mouse anti-Human GDF11 Monoclonal antibody (EML1029) | IHC-P | |
| MRO-1696-CN | Rabbit Anti-GDF11 Polyclonal Antibody (MRO-1696-CN) | IF, IHC, FC | Rabbit IgG |
| VS3-FY2115 | Rabbit Anti-GDF11 Recombinant Antibody (clone R41-2N-8) | WB, IHC-P, IF | Rabbit IgG |
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