Anti-Human GHR Recombinant Antibody (SS1)
CAT#: TAB-090CQ
Recombinant monoclonal antibody to GHR. SS1 is a humanized antibody that selectively interacts with and inhibits human GHR function. It can reduce IGF-1 levels. It can be potentially used in the treatment of arthritis.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & cytoplasmic bodies.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1366_E6_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane, cytosol & cytoplasmic bodies.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1639_F9_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane, cytosol & cytoplasmic bodies.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1361_E6_2_blue_red_green.jpg
Normal Tissue
Figure 4 Colon
Enterocytes - Microvilli
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (microvilli)
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (HSkMC, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112964-GHR
❮
❯
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Human, Cynomolgus monkey
- Clone
- SS1
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry
- Related Disease
- Arthritis
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TAB-090CQ. Click the button above to contact us or submit your feedback about this product.
Significant and Stable Signal
We used this product for IF test with a sample that we received three weeks ago. The data was good, demonstrating the success of our methodology and getting expected conclusion.
Good Specificity and Quality
We applied the anti-human GHR recombinant antibody (SS1) to both IF and IHC. The antibody's high affinity for the target antigen ensured stable binding, enhancing the reproducibility of experimental results.
Q&As
-
How about the affinity of the the anti-human GHR recombinant antibody (SS1)?
A: The anti-human GHR recombinant antibody (SS1) has high affinity for GHR. It is available to reduce the cross-reactivity through a direct conjugation.
-
Can the anti-human GHR recombinant antibody (SS1) be used for cells of other species besides humans?
A: Yes, the anti-human GHR recombinant antibody (SS1) has been validated for possessing the species reactivity with cynomolgus monkey.
-
Is the anti-human GHR recombinant antibody (SS1) effective in IF?
A: Yes, the anti-human GHR recombinant antibody (SS1) showed effectiveness in IF. The target protein exists in plasma membrane, cytosol and cytoplasmic bodies.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone SS1"
- CAT
- Product Name
See other products for "GHR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1090-VHH | Recombinant Anti-Human GHR VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2404z | Mouse Anti-GHR Recombinant Antibody (clone 43A10) | WB, Neut | Mouse IgG2b |
| MOB-2445MZ | Recombinant Mouse Anti-Rat GHR Antibody (clone NBC 374) | FC, IHC-Fr, IHC-P, IP | Mouse antibody |
| MRO-0696-CN | Rabbit Anti-GHR Recombinant Antibody (clone JU01-34) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0687J | Rabbit Anti-GHR Recombinant Antibody (clone 10C11) | ELISA, IHC, IF | Rabbit IgG |
| VS3-FY593 | Recombinant Rabbit Anti-GHR Antibody (clone R02-6E6) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-089CQ | Anti-Human GHR Recombinant Antibody (Ab13) | ELISA, FC | |
| TAB-089CQ-S(P) | Anti-Human GHR Recombinant Antibody scFv Fragment (Ab13) | ELISA, FC | |
| TAB-262CQ | Anti-Human GHR Recombinant Antibody (GF185) | FC, IP, Inhib | |
| TAB-262CQ-S(P) | Anti-Human GHR Recombinant Antibody scFv Fragment (GF185) | ELISA, FC, IP, WB | |
| TAB-262CQ-F(E) | Anti-Human GHR Recombinant Antibody Fab Fragment (GF185) | ELISA, FC, IP, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-091CQ | Anti-Human GHR Recombinant Antibody (SS3) | ELISA, FC | Humanized antibody |
| TAB-090CQ-S(P) | Anti-Human GHR Recombinant Antibody scFv Fragment (SS1) | ELISA, FC | Humanized antibody |
| TAB-091CQ-S(P) | Anti-Human GHR Recombinant Antibody scFv Fragment (SS3) | ELISA, FC | Humanized antibody |
| TAB-090CQ-F(E) | Anti-Human GHR Recombinant Antibody Fab Fragment (SS1) | ELISA, FC | Humanized antibody |
| TAB-091CQ-F(E) | Anti-Human GHR Recombinant Antibody Fab Fragment (SS3) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-875CQ | Mouse Anti-GHR Recombinant Antibody (clone CBL068) | WB, Neut | Mouse IgG2 |
| NEUT-876CQ | Mouse Anti-GHR Recombinant Antibody (clone CBL584) | WB, Neut | Mouse IgG2b |
| NEUT-877CQ | Mouse Anti-GHR Recombinant Antibody (clone MM0320-6J33) | WB, Neut | Mouse IgG2 |
| NEUT-878CQ | Mouse Anti-GHR Recombinant Antibody (clone MM0321-3C59) | WB, Neut | Mouse IgG2 |
| NEUT-879CQ | Mouse Anti-Ghr Recombinant Antibody (clone CBL586) | WB, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1438 | Hi-Affi™ Rabbit Anti-GHR Recombinant Antibody (clone DS1438AB) | WB, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY110 | AbPlus™ Anti-GHR Magnetic Beads (GF185) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC190 | Recombinant Anti-GHR Vesicular Antibody, EV Displayed (VS-0425-YC190) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2800 | Anti-Mouse GHR Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: WB, ELISA, IF
Application: IF, IP, Neut, FuncS, ELISA, FC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
