This product is a recombinant mouse anti-Hepatitis C virus monoclonal antibody (A10F2). A10F2 specifically binds to glycoprotein E2 associated with HCV and can be potentially used in the treatment and diagnosis of Hepatitis C virus infection.
Figure 1 Monoclonal antibody-mediated inhibition of HCV-LP binding to Huh 7 cells: HCV-LPs were incubated with mAbs (100 g/ml) for 1 h at RT and the mixture was added to Huh 7 cells.
The binding of HCV-LPs was evaluated by flow cytometry using anti-E1E2 polyclonal antibody followed by incubation with Alexa 488-conjugated anti-rabbit IgG. The x axis represents the mAbs and y axis represents percentage inhibition of HCV-LP binding.
Combination of neutralizing monoclonal antibodies against Hepatitis C virus E2 protein effectively blocks virus infection
Figure 2 Epitope localization of anti-HCV mAbs using truncated overlapping constructs.
Western blot analysis of recombinant E1 and E2 proteins.
Combination of neutralizing monoclonal antibodies against Hepatitis C virus E2 protein effectively blocks virus infection
Figure 3 Pre- (A-C) and post- (D-F) attachment neutralization assay: (A-C) The mAbs were pre-incubated with HCV-LPs for 1 h at RT and then the mixture was added to Huh 7 cells.
Huh 7 cells were incubated with HCV-LPs for 1 h at RT, followed by addition of the mAbs. The binding of HCV-LPs was monitored by flow cytometry.
Combination of neutralizing monoclonal antibodies against Hepatitis C virus E2 protein effectively blocks virus infection
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-446-F(E) | Recombinant Anti-HCV E2 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
HPAB-0195CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC3) | ELISA, Neut | Human Fab |
HPAB-0196CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC74) | ELISA, Neut | Human Fab |
HPAB-0197CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC46) | ELISA, Neut | Human Fab |
HPAB-0005-WJ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC-84.1) | ELISA, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-495 | Mouse Anti-HCV E2 Protein Recombinant Antibody (PABL-495) | ELISA, Neut | Mouse IgG |
PABL-496 | Recombinant Mouse Anti-HCV E2 Antibody (AP33) | FC, Neut, FuncS | IgG |
PABL-497 | Recombinant Human Anti-HCV E2 Antibody (AR3C) | Neut | IgG |
PABL-498 | Recombinant Human Anti-HCV E2 Antibody (C2) | Neut | IgG |
PABL-499 | Recombinant Human Anti-HCV E2 Antibody (HC33.8) | Neut | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-476LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-476LC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
MRO-476LC-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-476LC-S(P)) | ELISA | Mouse scFv |
MRO-476LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-476LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-477LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-477LC) | ELISA | Humanized IgG1, κ |
MRO-478LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-478LC) | ELISA | Humanized IgG1, κ |
MRO-477LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-477LC-F(E)) | ELISA | Humanized Fab |
MRO-478LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-478LC-F(E)) | ELISA | Humanized Fab |
MRO-479LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-479LC-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-485LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (AB 68) | ELISA | Human antibody |
MRO-488LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (CBH-4D) | ELISA, WB | Human antibody |
MRO-489LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (CBH-4B) | ELISA, WB | Human antibody |
MRO-490LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (CBH-4G) | ELISA, WB | Human antibody |
MRO-491LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (CBH-5) | ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1191LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (A10F2) | ELISA | Mouse Antibody |
MRO-1192LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (H6D3) | ELISA | Mouse Antibody |
MRO-1193LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (E3D8) | ELISA | Mouse Antibody |
MRO-1194LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (A7A6H9) | ELISA | Mouse Antibody |
MRO-1195LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (G9E1) | ELISA | Mouse Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC428 | PE-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM | |
MHC-LC429 | APC-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0065LC | Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) | ELISA | IgG1 |
EPAF-1294LC | Recombinant Human Anti-HCV E2 protein Antibody (4c2) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-415 | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (PSBC-415) | ELISA, FC, Neut | Human scFv |
FAMAB-0198JF-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone L1); scFv Fragment | WB, ELISA, FuncS | Human scFv |
FAMAB-0174WJ-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone 212.1.1); scFv Fragment | ELISA, WB, Neut | Human scFv |
PSBS-0067 | Human Anti-HCV E2 Recombinant Antibody (Clone HC84-26); scFv Fragment | ELISA, FuncS | Human scFv |
HPAB-1522WJ-S(P) | Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A8) | ELISA, WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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