Mouse Anti-HDGF Recombinant Antibody (clone C1) (CAT#: HPAB-0034-LSX)

Mouse antibody C1 provides methods of cancer therapy or diagnosis involving targeting hepatoma-derived growth factor (HDGF). The antibody may be used to inhibit HDGF, optionally coupled to or combined with other cancer therapies.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 Western blot analysis testing various monoclonal antibodies developed to against HDGF (lysate derived from H1944 cells).

Figure 1 Western blot analysis testing various monoclonal antibodies developed to against HDGF (lysate derived from H1944 cells).

Ren, H., Chu, Z., & Mao, L. (2009). Antibodies targeting hepatoma-derived growth factor as a novel strategy in treating lung cancer. Molecular cancer therapeutics, 8(5), 1106-1112.

IHC

Figure 2 Distribution ofthe antibodies in tumor tissue sections (detected by using specific antimouse IgG).

Figure 2 Distribution ofthe antibodies in tumor tissue sections (detected by using specific antimouse IgG).

Antibodies used were labeled on the side of each section for easy reference.

Ren, H., Chu, Z., & Mao, L. (2009). Antibodies targeting hepatoma-derived growth factor as a novel strategy in treating lung cancer. Molecular cancer therapeutics, 8(5), 1106-1112.

FuncS

Figure 3 Growth curves oftumors treated with various antibodies.

Figure 3 Growth curves oftumors treated with various antibodies.

Ren, H., Chu, Z., & Mao, L. (2009). Antibodies targeting hepatoma-derived growth factor as a novel strategy in treating lung cancer. Molecular cancer therapeutics, 8(5), 1106-1112.

FuncS

Figure 4 Tumor weight measured for each treatment groups. P values are based on comparisons with M31 control group.

Figure 4 Tumor weight measured for each treatment groups. P values are based on comparisons with M31 control group.

Ren, H., Chu, Z., & Mao, L. (2009). Antibodies targeting hepatoma-derived growth factor as a novel strategy in treating lung cancer. Molecular cancer therapeutics, 8(5), 1106-1112.


Specifications

  • Immunogen
  • HDGF
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Mouse HDGF
  • Species Reactivity
  • Mouse
  • Clone
  • C1
  • Applications
  • ELISA, WB, RIA, FC, ICC, IHC, FuncS
  • Related Disease
  • Lung cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Sections (4 Mm) were from formalin-fixed and paraffin-embedded tissue blocks or OCT-embedded frozen tissues. All the sections were mounted on positively charged glass slides. For formalin-fixed tissues, sections were deparaffinized and stained with appropriate antibody using ABC Elite system. For frozen tissues, the sections were fixed with acetone before being processed for staining. Diaminobenzidine was used as a chromogen and commercial hematoxylin was used for counterstaining. For microvessel density analysis, CD31 staining was measured using ×10 objective magnification for three to six randomly selected fields (2.18 mm2 per field). Each field was then divided into 155 squares (grids). The grids with CD31 staining was counted as positive and total positive grids divided by the total grids measured was used to calculate percentage of positive grids for each sample.

Target

  • Alternative Names
  • AI118077; D3Ertd299e

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone C1"

See other products for "HDGF"

Recombinant Antibody

CAT Product Name Application Type
MOB-2467z Mouse Anti-HDGF Recombinant Antibody (clone 33H7) ELISA, ICC, IF, IHC, WB Mouse IgG2a
MOB-0146CT Recombinant Mouse anti-Human HDGF Monoclonal antibody (37D5b) Dot, WB
HPAB-0032-LSX Mouse Anti-HDGF Recombinant Antibody (clone 2F12) ELISA, WB, IP, IF, ICC Mouse IgG1, κ
HPAB-0033-LSX Mouse Anti-HDGF Recombinant Antibody (clone H3) ELISA, WB, RIA, FC, ICC, IHC, FuncS Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1581 Rabbit Anti-HDGF Recombinant Antibody (clone DS1581AB) WB, IHC, ICC, IP, FC Rabbit IgG

scFv Fragment Antibody

Fab Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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