Recombinant Human Anti-HER2 Antibody (Gr6) (CAT#: PABX-082)
Anti-HER2 antibody is a Human antibody of IgG class that binds to an HER2. It developed From a synthetic human V (H) phage display library.
Specific Inquiry
Figure 1 Structure of Gr6
Ribbon diagramof theGr6 structure shown in cyan (chain A) and red (chain B). CDRs are colored in green in chain A and orange in chain
Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J., & Wang, S. (2012). Crystal structure of a human single domain antibody dimer formed through VH-VH non-covalent interactions. PloS one, 7(1), e30149.
Figure 2 Binding of Gr3 and Gr6 to HER2/Fc analyzed by SPR.
Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J., & Wang, S. (2012). Crystal structure of a human single domain antibody dimer formed through VH-VH non-covalent interactions. PloS one, 7(1), e30149.
Figure 3 Melting temperature (Tm) measurements of Gr3 and Gr6 by CD spectroscopy.
Melting temperature (Tm) measurements of Gr3 and Gr6 by CD spectroscopy. The CD values measured at 217 nm
are plotted against temperature ranging from 25uC to 91uC.
line shows the fitted values using
Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J., & Wang, S. (2012). Crystal structure of a human single domain antibody dimer formed through VH-VH non-covalent interactions. PloS one, 7(1), e30149.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human HER2
- Species Reactivity
- Human
- Clone
- Gr6
- Applications
- WB 1:1000-1:5000
ELISA 1:3000-1:15000
FuncS (assay dependent)
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
- Gene ID
- 2064
- UniProt ID
- P04626
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone Gr6"
See other products for "ERBB2"
Select a product category from the dropdown menu below to view related products.
Please select product type
Intrabody
Humanized Antibody
Chimeric Antibody
Immunotoxin
Fab Fragment Antibody
Single-domain Antibody
Human Antibody
Mouse Antibody
Fab Glycosylation
Fc Glycosylation
Deglycosylated Antibody (Non-glycosylated IgGs)
Chicken IgY Antibody
Blocking Antibody
Rabbit Monoclonal Antibody
Recombinant Antibody
ADCC Enhanced Antibody
MHC Tetramer for Cancer
scFv Fragment Antibody
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B008(A) | Recombinant Anti-human ERBB2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B008(G) | Recombinant Anti-human ERBB2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B008(T) | Recombinant Anti-human ERBB2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABX-082. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
-2.png)
Application: FC, IHC, FuncS, Inhib, Cyt
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
-1.jpg)
Application: WB, IHC, ELISA, FC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, IF, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
