Mouse Anti-HIV-1 Protease Recombinant Antibody (clone F11.2.32) (CAT#: PABL-195)
Recombinant Mouse Antibody (F11.2.32) is capable of binding to HIV-1 Protease, expressed in mammalian cells.
Specific Inquiry
Figure 1 Inhibition of HIV-1 protease activity by Fab F11.2.32.
The initial reaction velocity (vi), normalised to the initial reaction velocity in the absence of Fab (vo), is plotted as a function of Fab concentration. The protease was held at constant concentration (50 nM). The curve shows the best ®t of the tight-binding model (Williams & Morrison, 1979) to the experimental data, from which the deduced value of Kinh is 35(3) nM.
Lescar, J., Stouracova, R., Riottot, M. M., Chitarra, V., Brynda, J., Fabry, M.,... & Bentley, G. A. (1997). Three-dimensional structure of an fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody1.Journal of molecular biology, 267(5), 1207-1222.
Specifications
- Immunogen
- Human immunodeficiency virus type 1 Protease
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Tested positive against HIV-1 Protease
- Species Reactivity
- HIV-1
- Clone
- F11.2.32
- Applications
- WB, ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Inhib. For details, refer to published data.
Target
- Alternative Names
- peptidase; proteinase; Protease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-490 | Recombinant Anti-HIV-1 Protease Antibody | ELISA, IP, FuncS | IgG |
| MHH-490 | Recombinant Human Anti-HIV-1 Protease Antibody | ELISA, WB, IP, FuncS | IgG |
| PABL-194 | Mouse Anti-HIV-1 Protease Recombinant Antibody (clone 1696) | WB, ELISA, FuncS | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-490-F(E) | Recombinant Anti-HIV-1 Protease Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-490-F(E) | Recombinant Human Anti-HIV-1 Protease Antibody Fab Fragment | IF, ELISA, FuncS | Fab |
| PFBL-194 | Mouse Anti-HIV-1 Protease Recombinant Antibody (clone 1696); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| PFBL-195 | Mouse Anti-HIV-1 Protease Recombinant Antibody (clone F11.2.32); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-490-S(P) | Recombinant Anti-HIV-1 Protease Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| MHH-490-S(P) | Recombinant Human Anti-HIV-1 Protease Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| PSBL-194 | Mouse Anti-HIV-1 Protease Recombinant Antibody (clone 1696); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBL-195 | Mouse Anti-HIV-1 Protease Recombinant Antibody (clone F11.2.32); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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