Anti-HIV-1 gp120 Recombinant Antibody (F58/H3) (CAT#: MRO-042LC)

This product is a recombinant mouse anti-HIV-1 monoclonal antibody. F58/H3 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.

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WB

Figure 1 Western blot of peptide phages with the peptide expressed onphage cpIII stained with mAb F58/H3.

Figure 1 Western blot of peptide phages with the peptide expressed onphage cpIII stained with mAb F58/H3.

Lundin, K., Samuelsson, A., Jansson, M., Hinkula, J., Wahren, B., Wigzell, H., & Persson, M. A. A. (1996). Peptides isolated from random peptide libraries on phage elicit a neutralizing anti‐HIV‐1 response: analysis of immunological mimicry. Immunology, 89(4), 579-586.

ELISA

Figure 2 Inhibition of binding of mAb F58/H3 to recombinant gp120 inELISA: mAb, 0.5mg/ml, was mixed with different concentrations of (a)peptide phages or (b) synthetic peptides, and incubated on gp120 coatedplates.

Figure 2 Inhibition of binding of mAb F58/H3 to recombinant gp120 inELISA: mAb, 0.5mg/ml, was mixed with different concentrations of (a)peptide phages or (b) synthetic peptides, and incubated on gp120 coatedplates.

Lundin, K., Samuelsson, A., Jansson, M., Hinkula, J., Wahren, B., Wigzell, H., & Persson, M. A. A. (1996). Peptides isolated from random peptide libraries on phage elicit a neutralizing anti‐HIV‐1 response: analysis of immunological mimicry. Immunology, 89(4), 579-586.


Specifications

  • Immunogen
  • HIV envelope gp120
  • Host Species
  • Mouse
  • Type
  • Mouse antibody
  • Specificity
  • HIV-1
  • Clone
  • F58/H3
  • Applications
  • WB, ELISA
  • Related Disease
  • AIDS

Applications

  • Application Notes
  • The HIV-1 gp120 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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