Anti-HIV-1 gp120 Recombinant Antibody (P4/D10) (CAT#: MRO-044LC)

This product is a recombinant mouse anti-HIV-1 monoclonal antibody. P4/D10 specifically binds to gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.

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ELISA

Figure 1 Effect of single amino acid deletions on mAb reactivity to the neutralization-inducing site.

Figure 1 Effect of single amino acid deletions on mAb reactivity to the neutralization-inducing site.

Broliden, P. A., Mäkitalo, B., Akerblom, L., Rosen, J., Broliden, K., Utter, G., ... & Wahren, B. (1991). Identification of amino acids in the V3 region of gp120 critical for virus neutralization by human HIV-1-specific antibodies. Immunology, 73(4), 371.


Specifications

  • Immunogen
  • HIV envelope gp120
  • Host Species
  • Mouse
  • Type
  • Mouse antibody
  • Specificity
  • HIV-1
  • Clone
  • P4/D10
  • Applications
  • ELISA
  • Related Disease
  • AIDS

Applications

  • Application Notes
  • The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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