Anti-HIV-1 gp120 Recombinant Antibody (BAT085) (CAT#: MRO-134LC)
This product is a recombinant mouse anti-HIV-1 monoclonal antibody (BAT085). BAT085 specifically binds to CD4 binding site of gp120 and can be potentially used in the treatment studies of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
Specific Inquiry
ELISA
Figure 2. Inhibition of the binding of biotinylated BAT085 (△) to captured HIV-1 IIIB gpl20 in ELISA.
Fung, M. S., Sun, C. R., Gordon, W. L., Liou, R. S., Chang, T. W., Sun, W. N., ... & Ho, D. D. (1992). Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120. Journal of virology, 66(2), 848-856.
Neut
Figure 4 is a plot showing the relative effectiveness of four of the monoclonal antibodies of the invention in neutralizing HIV-1 infection of H9 cells.
The percentage of infected cells was determined thirteen days after infection.
Specifications
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- HIV-1
- Clone
- BAT085
- Applications
- ELISA, WB, IF, Neut
- Related Disease
- AIDS
Applications
- Application Notes
- The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Immunofluorescence, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
| PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
| PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (PABL-521) | ELISA, Neut | Human IgG |
| PABL-522 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-VRC01.H5.F-185917) | WB, FuncS | Human IgG |
| PABL-523 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 8ANC131) | WB, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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