Human Anti-HIV-1 V3 Recombinant Antibody (clone 3074) (CAT#: PABL-570)

Recombinant Human Antibody (3074) is capable of binding to HIV-1 V3, expressed in HEK 293 cells.


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Figure 1 Neutralization curves of anti-V3 mAb 3074 against representative HIV-1 psVs tested using the U87 target cell.

Figure 1 Neutralization curves of anti-V3 mAb 3074 against representative HIV-1 psVs tested using the U87 target cell.

Anti-V3 mAb 3074 weas tested for neutralization against HIV-1 pseudoviruses using the U87 cell line as target cells. The titration curves from eight selected psVs and the aMLV psV control are shown.

Hioe, C. E., Wrin, T., Seaman, M. S., Yu, X., Wood, B., Self, S., ... & Zolla-Pazner, S. (2010). Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes. PloS one, 5(4), e10254.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1,λ
  • Specificity
  • HIV-1
  • Species Reactivity
  • HIV-1
  • Clone
  • 3074
  • Applications
  • WB 1:1000-1:10000
    ELISA 1:1000-1:20000
    Neut Assay-dependent
    FuncS Assay-dependent

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Assay-dependent

Target

  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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