Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 11f10) (CAT#: PABL-559)

Recombinant Mouse Antibody (11f10) is capable of binding to HIV-1 gp41, expressed in mammalian cells.

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Figure 1 11F10 mAb interaction with gp41-inter and recombinant gp41 proteins.

Figure 1 11F10 mAb interaction with gp41-inter and recombinant gp41 proteins.

SPR sensogram of binding of 11F10 mAb at 2 (red), 5 (blue), 10 (green) and 20 (gray) µg/ml concentration to (A) GCN4-gp41 inter, (B) 92UG gp41-inter and (C) recombinant gp41 MN immobilized on a Biacore CM5 chip is shown. The binding curves were fitted globally to a 1∶1 Langmuir model to obtain the displayed rate constants and dissociation constant. The best fit are overlaid in black.

Dennison, S. M., Sutherland, L. L., Jaeger, F. H., Anasti, K. M., Parks, R., Stewart, S., ... & Scearce, R. M. (2011). Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41. PloS one, 6(11), e27824.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Tested positive against HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • 11f10
  • Applications
  • WB 1:1000-1:10000
    ELISA 1:1000-1:20000
    FuncS Assay-dependent

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Assay-dependent

Target

  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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