Recombinant Mouse Antibody (11f10) is capable of binding to HIV-1 gp41, expressed in mammalian cells.
Figure 1 11F10 mAb interaction with gp41-inter and recombinant gp41 proteins.
SPR sensogram of binding of 11F10 mAb at 2 (red), 5 (blue), 10 (green) and 20 (gray) µg/ml concentration to (A) GCN4-gp41 inter, (B) 92UG gp41-inter and (C) recombinant gp41 MN immobilized on a Biacore CM5 chip is shown. The binding curves were fitted globally to a 1∶1 Langmuir model to obtain the displayed rate constants and dissociation constant. The best fit are overlaid in black.
Dennison, S. M., Sutherland, L. L., Jaeger, F. H., Anasti, K. M., Parks, R., Stewart, S., ... & Scearce, R. M. (2011). Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41. PloS one, 6(11), e27824.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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PABL-558 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8066) | WB, Neut | Human IgG |
PABL-560 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 6a7) | WB, ELISA, FuncS | Mouse IgG |
PABL-561 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone mAb1281) | ELISA, Neut | Human IgG |
PABL-562 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone NC-1) | WB, ELISA, FC, FuncS | Mouse IgG2a,κ |
MRO-849CQ | Human Anti-HIV-1 gp41 Recombinant Antibody (MRO-849CQ) | ELISA | Human IgG1, λ |
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