Recombinant Human Anti-HLA-A Antibody (T1) (CAT#: PABX-105)
Anti-HLA-A antibody is a Human antibody of IgG class that binds to an HLA-A. This antibody achieved 2-to 4-nM affinities to HIV-2.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Crystal structure of T1 Fab binding HLA-A2/NYESO1, with highlighting of targeted amino acids.
Maus, M. V., Plotkin, J., Jakka, G., Stewart-Jones, G., Rivière, I., Merghoub, T., ... & Sadelain, M. (2016). An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity. Molecular Therapy-Oncolytics, 3, 16023.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human HLA-A
- Species Reactivity
- Human
- Clone
- T1
- Applications
- Can be useful in applications such as: Western blot; Enzyme-linked Immunosorbent Assay; Functional Study
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain
- Gene ID
- 3105
- UniProt ID
- P30443
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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PFBC-072 | Human Anti-HLA-A Recombinant Antibody (clone HYB3); Fab Fragment | WB, ELISA | Human Fab |
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