Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8); scFv Fragment (CAT#: HPAB-0026-YC-S(P))
The anti-HLA-DR antibody that recognizes the human leucocyte antigen-DR (HLA-DR), which is a cell membrane molecule associated with immunity. And anti-HLA-DR antibody can be as a preventive or therapeutic agent for immune responses caused by an HLA-DR-expressing cell, especially, a therapeutic agent for chronic rheumatism.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human HLA-DRB1
- Species Reactivity
- Human, Mouse
- Clone
- HD8
- Applications
- Cyt, WB
- Related Disease
- Malignant tumor, Chronic rheumatism
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HLA-DRB1; major histocompatibility complex, class II, DR beta 1; SS1; DRB1; HLA-DRB; HLA-DR1B
- Gene ID
- 3123
- UniProt ID
- Q5Y7D1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1090z-F(E) | Recombinant Anti-Human HLA-DRB1 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| HPAB-0023-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0024-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0025-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); Fab Fragment | Cyt, WB | Human Fab |
| HPAB-0026-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8); Fab Fragment | Cyt, WB | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1090z-S(P) | Recombinant Anti-Human HLA-DRB1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-0023-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0024-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0025-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); scFv Fragment | Cyt, WB | Human scFv |
| HPAB-0086-FY-S(P) | Mouse Anti-HLA-DRB1 Recombinant Antibody; scFv Fragment (HPAB-0086-FY-S(P)) | WB | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-150 | Anti-Human HLA DR beta Recombinant Antibody (Apolizumab) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1623 | Rabbit Anti-HLA-DRB1 Recombinant Antibody (clone DS1623AB) | WB, IHC, ICC | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3346 | PE-DRB1*04:01/Human HLA-DRB1 (VYPEVTVYPAKT) MHC Tetramer | FCM |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0023-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33) | ELISA | Humanized IgG |
| HPAB-0024-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33) | ELISA | Humanized IgG |
| HPAB-0025-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4) | Cyt, WB | Human IgG |
| HPAB-0026-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8) | Cyt, WB | Human IgG |
| VS3-FY681 | Recombinant Mouse Anti-HLA-DRB1 Antibody (clone 5B3D2) | ELISA, IHC, FC | Mouse IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-150 | Afuco™ Anti-HLA-DRB1 ADCC Recombinant Antibody (Apolizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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