Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33) (CAT#: HPAB-0023-YC)
The monoclonal antibody antigen is a transmembrane glycoprotein expressed in normal colonic and bowel epithelium and human colon cancers. A humanized version of mAb may be characterized to identify epitopes relating to the observed immune response in humans as a therapeutic antibody.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human HLA-DRB1
- Species Reactivity
- Human
- Clone
- huA33
- Applications
- ELISA
- Related Disease
- Colon cancers
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HLA-DRB1; major histocompatibility complex, class II, DR beta 1; SS1; DRB1; HLA-DRB; HLA-DR1B
- Gene ID
- 3123
- UniProt ID
- Q5Y7D1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone huA33"
See other products for "HLA-DRB1"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Humanized Antibody Products
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
ADCC Enhanced Antibody Products
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1090z | Mouse Anti-HLA-DRB1 Recombinant Antibody (MOB-1090z) | WB, IHC, IF, FC | Mouse IgG2b, κ |
| HPAB-0024-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33) | ELISA | Humanized IgG |
| HPAB-0025-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4) | Cyt, WB | Human IgG |
| HPAB-0086-FY | Mouse Anti-HLA-DRB1 Recombinant Antibody (HPAB-0086-FY) | FC, WB, EM, Cyt | Mouse IgG1 |
| VS3-XY3381 | Rabbit Anti-HLA-DRB1 Recombinant Antibody (clone R02-4K1) | WB, IHC-P, ICC, IF | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0023-YC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: Block, Cyt, FuncS, Inhib
Application: ELISA, IP, WB, IHC, IF, FuncS
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, IF, IHC, WB
Application: IF, IP, Neut, FuncS, ELISA, FC
Application: ELISA, IHC, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
