Recombinant Human Anti-HMPV Antibody scFv Fragment (DS7) (CAT#: PABX-106-S (P))

Anti-HMPV antibody is a Human of scFv class that binds to an HMPV. This antibody is shows subnanomolar affinity and is highly protective in vivo. It developed From a human antibody phage display library.


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Figure 1 Light-microscopic and immunofluorescent images of hMPV-infected LLC-MK2 cell monolayers stained with human anti-hMPV F Fab and AlexaFluor569-conjugated goat anti-human IgG.

Figure 1 Light-microscopic and immunofluorescent images of hMPV-infected LLC-MK2 cell monolayers stained with human anti-hMPV F Fab and AlexaFluor569-conjugated goat anti-human IgG.

(A and B) Fab ACN044; (C and D) Fab DS7. Magnification, × 21.

Williams, J. V., Chen, Z., Cseke, G., Wright, D. W., Keefer, C. J., Tollefson, S. J., ... & Burton, D. R. (2007). A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutica

Figure 2 SPR analysis of DS8 Fab.

Figure 2 SPR analysis of DS8 Fab.

(A) Association-dissociation curves of decreasing concentrations of DS7 against immobilized hMPV FTM protein. Palivizumab (RSV F-specific MAb) was used as an irrelevant control. (B) Association-dissociation curves of DS7 at 101 nM against immobilized hMP㜮㌮㐮㄀㌮㘮ㄮ㔮㔮㜮㌮㈮㄀㌮㘮ㄮ㔮㔮㜮㌮㌮㄀㌮㘮ㄮ㔮㔮㜮㌮㤮㄀㌮㘮ㄮ㔮㔮

Williams, J. V., Chen, Z., Cseke, G., Wright, D. W., Keefer, C. J., Tollefson, S. J., ... & Burton, D. R. (2007). A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeuticaW


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • scFv
  • Specificity
  • Tested positive against native Human CEA
  • Species Reactivity
  • Human metapneumovirus
  • Clone
  • DS7
  • Applications
  • WB 1:1000-1:5000
    ELISA 1:3000-1:15000
    FuncS (assay-depended)

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • Assay-depended

Target

  • Alternative Names
  • Human metapneumovirus; hMPV

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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