Anti-Human CD200 Recombinant Antibody (Samalizumab) (CAT#: TAB-210)
Recombinant monoclonal antibody to CD200. Samalizumab is a humanized monoclonal antibody designed for oncology indications.
Specific Inquiry
Figure 1 Examples of well- to poorly differentiated transitional cell carcinoma of the human bladder (TCC) (A, C, E, G) with corresponding immunostaining of CD200 (B, D, F, H).
A and B: Well-differentiated low-grade TCC and the corresponding immunohistological staining with antiCD200 with score 0. C and D: Intermediately differentiated low-grade TCC, with anti-CD200 score 1. E and F: Poorly differentiated high-grade TCC, with anti-CD200 score 2. G and H: Poorly differentiated high-grade TCC, with anti-CD200 score 3. Hematoxylin-eosin, magnification ×200.
REXIN, P., TAUCHERT, A., HÄNZE, J., HEERS, H., SCHMIDT, A., HOFMANN, R., & HEGELE, A. (2018). The Immune Checkpoint Molecule CD200 Is Associated with Tumor Grading and Metastasis in Bladder Cancer. Anticancer research, 38(5), 2749-2754.
Figure 2 Exemplary analysis of CD200 expression in transitional cell carcinoma (TCC) tumor tissue (Tumor) and TCC cell lines (T24 and UMUC3).
Quantitative analysis of CD200 mRNA by quantitative reverse transcription polymerase chain reaction relative to β-actin mRNA (ΔCt; log-2-scale). Representative single values per sample are displayed.
REXIN, P., TAUCHERT, A., HÄNZE, J., HEERS, H., SCHMIDT, A., HOFMANN, R., & HEGELE, A. (2018). The Immune Checkpoint Molecule CD200 Is Associated with Tumor Grading and Metastasis in Bladder Cancer. Anticancer research, 38(5), 2749-2754.
Figure 3 Exemplary analysis of CD200 expression in transitional cell carcinoma (TCC) tumor tissue (Tumor) and TCC cell lines (T24 and UMUC3).
Immunodetection of CD200 by western blot analysis. The molecular weight of protein marker is indicated (kDa).
REXIN, P., TAUCHERT, A., HÄNZE, J., HEERS, H., SCHMIDT, A., HOFMANN, R., & HEGELE, A. (2018). The Immune Checkpoint Molecule CD200 Is Associated with Tumor Grading and Metastasis in Bladder Cancer. Anticancer research, 38(5), 2749-2754.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG2 / G4 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC, WB
- CAS
- 1073059-33-2
- Generic Name
- Samalizumab
- MW
- 147.7 kDa
- Related Disease
- Blood cancers
Product Property
- Purity
- >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- At -20°C for one year.
Applications
- Application Notes
- The CD200 antibody has been reported in applications of IHC, RT-PCR, WB.
Target
- Alternative Names
- Samalizumab;1073059-33-2;Anti-CD200;ALXN6000;CD200;CD200 molecule;antigen identified by monoclonal MRC OX 2 , CD200 antigen , MOX1, MOX2;OX-2 membrane glycoprotein;MRC;OX 2;CD200 antigen;MRC OX-2 antigen;antigen identified by monoclonal MRC OX-2;MOX1;MOX2
- Gene ID
- 4345
- UniProt ID
- P41217
Related Resources
Please refer to Samalizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Samalizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Samalizumab"
Afuco™ Anti-CD200 ADCC Recombinant Antibody (Samalizumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD200. Samalizumab is a humanized monoclonal antibody designed for oncology indications.
See other products for "CD200"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2283MZ | Mouse Anti-CD200 Recombinant Antibody (clone NSD PY-3) | FC | Mouse IgG1 |
| HPAB-0365LY | Mouse Anti-CD200 Recombinant Antibody (HPAB-0365LY) | IHC | Mouse IgG2 |
| HPAB-0259-YJ | Human Anti-CD200 Recombinant Antibody (HPAB-0259-YJ) | FC, ELISA, FuncS | Chimeric (Mouse/Human) IgG1, κ |
| HPAB-0260-YJ | Human Anti-CD200 Recombinant Antibody (HPAB-0260-YJ) | FC, ELISA, FuncS | Humanized IgG1, κ |
| FAMAB-1618CQ | Mouse Anti-CD200 Recombinant Antibody (clone OX2) | FC | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-302CQ | Mouse Anti-CD200 Recombinant Antibody (clone CBL014) | Neut | Mouse IgG1 |
| NEUT-304CQ | Mouse Anti-CD200 Recombinant Antibody (clone 2K50) | Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-303CQ | Mouse Anti-CD200 Recombinant Antibody (clone OX-104) | FC, IHC, Block | Mouse IgG1, κ |
| NEUT-305CQ | Mouse Anti-CD200 Recombinant Antibody (clone CBL367) | ELISA, Block | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4025 | Hi-Affi™ Rabbit Anti-CD200 Recombinant Antibody (clone SI90DS) | IHC-P | Rabbit IgG |
| MOR-4026 | Hi-Affi™ Rabbit Anti-CD200 Recombinant Antibody (clone SI91DS) | FC | Rabbit IgG |
| MOR-4027 | Hi-Affi™ Rabbit Anti-CD200 Recombinant Antibody (clone SI92DS) | FC | Rabbit IgG |
| MOR-4028 | Hi-Affi™ Rabbit Anti-CD200 Recombinant Antibody (clone SI93DS) | ELISA | Rabbit IgG |
| MOR-4029 | Hi-Affi™ Rabbit Anti-CD200 Recombinant Antibody (clone SI94DS) | ELISA | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0365LY-S(P) | Mouse Anti-CD200 Recombinant Antibody; scFv Fragment (HPAB-0365LY-S(P)) | IHC | Mouse scfv |
| HPAB-0259-YJ-S(P) | Mouse Anti-CD200 Recombinant Antibody; scFv Fragment (HPAB-0259-YJ-S(P)) | FC, ELISA, FuncS | Mouse scFv |
| HPAB-0260-YJ-S(P) | Human Anti-CD200 Recombinant Antibody; scFv Fragment (HPAB-0260-YJ-S(P)) | FC, ELISA, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0365LY-F(E) | Mouse Anti-CD200 Recombinant Antibody; Fab Fragment (HPAB-0365LY-F(E)) | IHC | Mouse Fab |
| HPAB-0259-YJ-F(E) | Human Anti-CD200 Recombinant Antibody; Fab Fragment (HPAB-0259-YJ-F(E)) | FC, ELISA, FuncS | Human Fab |
| HPAB-0260-YJ-F(E) | Human Anti-CD200 Recombinant Antibody; Fab Fragment (HPAB-0260-YJ-F(E)) | FC, ELISA, FuncS | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-210 | Afuco™ Anti-CD200 ADCC Recombinant Antibody (Samalizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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