Anti-Human CD4 Recombinant Antibody (TAB-171) (CAT#: TAB-171)
Recombinant monoclonal antibody to CD4. It is a monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg
Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
Specifications
- Immunogen
- Recombinant fragment (Human) corresponding to the external domain.
- Host Species
- primate
- Derivation
- Chimeric (primate/human)
- Type
- IgG1 - lambda
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
- Related Disease
- Rheumatoid arthritis (RA)
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Keliximab;174722-30-6;IDEC CE9.1;SB210396;CD4;CD4 molecule;CD4 antigen (p55) , T cell surface glycoprotein CD4;T-cell surface glycoprotein CD4;CD4 receptor;CD4 antigen (p55);T-cell surface antigen T4/Leu-3;CD4mut;
- Gene ID
- 920
- UniProt ID
- P01730
Related Resources
Please refer to Keliximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Keliximab.
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1067z | Mouse Anti-CD4 Recombinant Antibody (clone 34D6) | FC, FuncS, ICC, IF, IP, WB | Mouse IgG2b, κ |
| PABL-426 | Human Anti-CD4 Recombinant Antibody (clone 576) | WB, ELISA, FuncS | Human IgG |
| PABL-427 | Human Anti-CD4 Recombinant Antibody (clone Hu5A8) | ELISA, Cyt, WB, Neut | Human IgG4 |
| MOB-0272MZ | Mouse Anti-CD4 Recombinant Antibody (clone 5C13) | IHC | Mouse IgG1 |
| HPAB-0792-CN | Mouse Anti-CD4 Recombinant Antibody (clone B4) | ELISA | Mouse IgG |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-171, RRID: AB_3111847)
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