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Keliximab (TAB-171)

Recombinant monoclonal antibody to CD4. Keliximab is a monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4. The drug is a chimeric antibody from Macaca irus and Homo sapiens.      
  • Datasheet

Specifications
Immunogen
Recombinant fragment (Human) corresponding to the external domain.
Host
primate
Derivation
Chimeric (primate/human)
Type
IgG1 - lambda
Specificity
Tested positive against native human antigen.
Species Reactivity
Human
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS NO.
174722-30-6
Generic Name
Keliximab
Related Disease
Rheumatoid arthritis (RA)
Target
Alternative Names
Keliximab; 174722-30-6; IDEC CE9.1; SB210396; CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4
Entrez Gene ID
920
UniProt ID
P01730

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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