Recombinant Mouse anti-Human CFTR Monoclonal antibody (N4B8) (CAT#: MOB-0481CT)
Recombinant Mouse monoclonal antibody to Human CFTR, expressed in Chinese Hamster Ovary cells(CHO).
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Normal Tissue
RNA Expression
Figure 1 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3_val_selected.jpg
Figure 2 Low expression in skeletal muscle.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1951/160344_B_3_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1951/160344_B_3_6_val_selected.jpg
Figure 3 Low expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_9_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_9_8_val_selected.jpg
Figure 4 Pancreas
(Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3.jpg
(Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3.jpg
Figure 5 RNA cell line category: Group enriched (CACO-2, MOLT-4, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000001626-CFTR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000001626-CFTR
Specifications
- Immunogen
- Recombinant protein encoding NBF 2 domain of human CFTR.
- Host Species
- Mouse
- Specificity
- This antibody reacts with a protein of 165-170 kDa.
- Species Reactivity
- Human
- Clone
- N4B8
- Applications
- Used for immunoassay techniques such as: Flow Cytometry; Immunohistochemistry (Frozen sections); Immunohistochemistry paraffin embedded sections
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 0.1 mg/ml
- Buffer
- Preservative: 0.05% Sodium Azide Constituents: 1% BSA, Ascites
- Storage
- Store at +4°C.
Target
- Alternative Names
- CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1; cystic fibrosis transmembrane conductance regulator; cAMP-dependent chloride channel; channel conductance-controlling ATPase;
- Gene ID
- 1080
- UniProt ID
- P13569
- Protein Refseq
- NP_000483
- Function
- ATP binding; ATP-binding and phosphorylation-dependent chloride channel activity; ATPase activity; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; hydrolase activity; ion channel activity; nu
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1704z | Mouse Anti-CFTR Recombinant Antibody (clone 28C12) | WB, IF, IHC | Mouse IgG1 |
| MRO-1772-CN | Rabbit Anti-CFTR Polyclonal Antibody (MRO-1772-CN) | WB, IF, IHC, FC | Rabbit IgG |
| PABS-0273 | Camelid Anti-CFTR Recombinant Antibody (PABS-0273) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, pull-down, ELISA, FuncS | Camelid VHH |
| PABS-0274 | Camelid Anti-CFTR Recombinant Antibody (clone G3a) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, Pull-down, ELISA, FuncS | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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