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    Anti-Human DLL4 Recombinant Antibody (TAB-204) (CAT#: TAB-204)

    Recombinant monoclonal antibody to DLL4. It is a humanized monoclonal antibody designed for the treatment of cancer.

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    • Endotoxin:

    • Purity:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human small intestine
    Figure 1 IHC staining of human small intestine
    (Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_2_selected.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_9_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_6.jpg
    RNA Expression
    Figure 6 RNA cell line category: Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)
    Figure 6 RNA cell line category: Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128917-DLL4

    Specifications

    • Immunogen
    • Partial recombinant DLL4 ragment.
    • Host Species
    • Mouse
    • Derivation
    • Humanized (from mouse)
    • Type
    • IgG2 - kappa
    • Specificity
    • Tested positive against native human antigen.
    • Species Reactivity
    • Human
    • Applications
    • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
    • MW
    • 145.3 kDa
    • Related Disease
    • Cancers

    Product Property

    • Purity
    • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Target

    • Alternative Names
    • Demcizumab;1243262-17-0;OMP-21M18;DLL4;delta-like 4 (Drosophila);delta like 4 homolog (Drosophila);delta-like protein 4;delta4;delta 4;delta ligand 4;notch ligand DLL4;delta-like 4 homolog;delta-like 4 protein;notch ligand delta-2;drosophila Delta homolog

    Related Resources

    • Biosimilar Overview
    Please refer to Demcizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Demcizumab.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "DLL4"

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    Rat Antibody Products Chimeric Antibody Products Mouse Antibody Products Human Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products Antibody Magnetic Beads ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-217CL Human Anti-DLL4 Recombinant Antibody (TAB-217CL) WB, IHC, IF, FC, Inhib Human IgG

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    Cite This Product

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    (Creative Biolabs Cat# TAB-204, RRID: AB_3111872)

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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