Recombinant Mouse anti-Human DSP Monoclonal antibody (FQ2999Z) (CAT#: MOB-2370CT)
Recombinant Mouse Monoclonall antibody to Human DSP, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37324/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37324/if_selected.jpg
Figure 2 Skin 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/45840/136491_B_7_1_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/45840/136491_B_7_1_selected.jpg
Figure 3 Skin
(Cells in basal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25% Langerhans cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37324/70857_B_8_1.jpg
(Cells in basal layer Staining: Medium Intensity: Moderate Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Eccrine glands Staining: Medium Intensity: Moderate Quantity: 75%-25% Langerhans cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37324/70857_B_8_1.jpg
Figure 4 RNA cell line category: Cell line enhanced (BEWO, HaCaT, HBEC3-KT, hTCEpi, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096696-DSP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096696-DSP
Specifications
- Immunogen
- Full length protein (Cow).
- Host Species
- Mouse
- Specificity
- Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.
- Species Reactivity
- Human
- Clone
- FQ2999Z
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry; Immunocytochemistry/Immunofluorescence; Western Blot; Immunohistochemistry (Frozen sections)
- Conjugate
- Unconjugated
Product Property
- Purity
- Immunogen affinity purified
- Format
- Liquid
- Buffer
- Preservative: 0.1% Sodium Azide. Constituents: 0.5% BSA, PBS, pH 7.4
- Storage
- Add glycerol to a final volume of 50%, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- DSP; desmoplakin; DP; DPI; DPII; DCWHKTA; desmoplakin I; desmoplakin II; 250/210 kDa paraneoplastic pemphigus antigen;
- Gene ID
- 1832
- UniProt ID
- P15924
- Protein Refseq
- NP_004406
- Function
- protein binding; protein binding, bridging; structural constituent of cytoskeleton; structural molecule activity;
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2025z | Mouse Anti-DSP Recombinant Antibody (clone 41G1) | WB, ICC, IF, IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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