Recombinant Mouse anti-Human ERCC1 Monoclonal antibody (3437D2b)
CAT#: MOB-0690CT
Recombinant Mouse monoclonal antibody to Human ERCC1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50182/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72859/157426_A_4_1_selected.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72860/157430_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Preleptotene spermatocytes Staining: Medium Intensity: Strong Quantity: <25% Round or early spermatids Staining: Medium Intensity: Strong Quantity: <25% Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72860/157430_A_5_6.jpg
Normal Tissue
Figure 5 Heart muscle
Cardiomyocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72860/157430_B_5_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72860/157430_A_8_8.jpg
Normal Tissue
Figure 7 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72860/157430_B_7_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000012061-ERCC1
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Specifications
- Immunogen
- Recombinant fragment from a region of human ERCC1
- Host Species
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Clone
- 3437D2b
- Applications
- Used for immunoassay techniques such as: Dot blot; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.1 mg/ml
- Buffer
- Preservative: 0.05% Sodium Azide Constituents: 1% BSA, PBS
- Storage
- Store at +4°C.
Target
- Alternative Names
- ERCC1; excision repair cross-complementation group 1; UV20; COFS4; RAD10; DNA excision repair protein ERCC-1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence);
- Gene ID
- 2067
- UniProt ID
- P07992
- Protein Refseq
- NP_001159521
- Function
- damaged DNA binding; damaged DNA binding; endonuclease activity; hydrolase activity; protein C-terminus binding; protein binding; protein domain specific binding; single-stranded DNA binding; contributes_to single-stranded DNA specific endodeoxyribonuclea
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1931z | Mouse Anti-ERCC1 Recombinant Antibody (clone 21G8) | WB, ICC, IF, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
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| MOR-1183 | Hi-Affi™ Rabbit Anti-ERCC1 Recombinant Antibody (clone DS1183AB) | FC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MRO-0541-CN | Rabbit Anti-ERCC1 Recombinant Antibody (clone JM10-07) | WB, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| ZG-0020C | Mouse Anti-ERCC1 Recombinant Antibody (clone 1B10) | WB, IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0021C | Mouse Anti-ERCC1 Recombinant Antibody (clone PT0756) | WB, IF, ICC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0314J | Mouse Anti-ERCC1 Recombinant Antibody (ZG-0314J) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2341 | Anti-ERCC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY2342 | Anti-Mouse ERCC1 Immunohistochemistry Kit | IHC |
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