Recombinant Mouse anti-Human FGFR2 Monoclonal antibody (EML2262)
CAT#: MOB-0737CT
Recombinant Mouse monoclonal antibody to Human FGFR2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm, cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human skin
Immunohistochemical staining of human skin shows strong ctyoplasmic positivity in keratinocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, CACO-2, HaCaT, HAP1, NTERA-2, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000066468-FGFR2
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Specifications
- Immunogen
- Recombinant fragment, corresponding to amino acids 621-724 of Human FGFR2
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML2262
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- Batch dependent within range:0.5 -1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14;
- Gene ID
- 2263
- UniProt ID
- P21802
- Protein Refseq
- NP_000132
- Function
- ATP binding; fibroblast growth factor binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast growth factor-activated receptor activity; fibroblast growth factor-activated receptor activity; heparin bind
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-057WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-057WM-S(P)) | ELISA, FC, Block | Human scFv |
| TAB-057WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-057WM-F(E)) | ELISA, FC, Block | Humanized Fab |
| CAT | Product Name | Application | Type |
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| TAB-060WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
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| TAB-060WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
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| CAT | Product Name | Application | Type |
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| NS-027CN-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); scFv Fragment | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-AP348-YC | Human Anti-FGFR2 Recombinant Antibody (HPAB-AP348-YC) | ELISA, FC, Neut, ADCC, FuncS | Chimeric (rat/human) IgG |
| HPAB-AP349-YC | Human Anti-FGFR2 Recombinant Antibody (HPAB-AP349-YC) | ELISA, FC, Neut, ADCC, FuncS | Chimeric (rat/human) IgG |
| HPAB-AP350-YC | Rat Anti-FGFR2 Recombinant Antibody (HPAB-AP350-YC) | ELISA, FC, Neut, ADCC, FuncS | Rat IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-0675-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M017-B02); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0676-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M021-H02); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0677-WJ-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M054-D03); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0674-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M047-D08); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0675-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M017-B02); Fab Fragment | ELISA, FC | Human Fab |
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