Recombinant Mouse anti-Human GNB2L1 Monoclonal antibody (2D8)
CAT#: MOB-2353CT
Recombinant Mouse Monoclonall antibody to Human GNB2L1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 18 Cerebral cortex
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21676/299_D4_2_selected.jpg
Subcellular Location
Figure 19 Cerebral cortex
Immunohistochemical staining of human breast shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_B_2_4_selected.jpg
Normal Tissue
Figure 20 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_B_8_5.jpg
Normal Tissue
Figure 21 Cerebral cortex
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_7_3.jpg
Normal Tissue
Figure 22 Cerebral cortex
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_8_7.jpg
Normal Tissue
Figure 23 Cerebral cortex
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_8_8.jpg
RNA Expression
Figure 24 Cerebral cortex
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204628-RACK1
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Specifications
- Immunogen
- A synthetic peptide from the internal part of human RACK1 conjugated to an immunogenic carrier protein. The peptide is homologous in many species including rat, mouse and xenopus.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 2D8
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Western Blot; Immunohistochemistry paraffin embedded sections; Immunohistochemistry (Frozen sections)
- Conjugate
- Unconjugated
Product Property
- Purity
- Whole antiserum
- Format
- Liquid
- Buffer
- Preservative: None. Constituents: Whole serum
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1; guanine nucleotide-binding protein subunit beta-2-like 1; lung cancer oncogene 7; proliferation-inducing gene 21; receptor for activated C kinase 1; human lung cancer oncogene 7 protein; receptor of activated protein kinase C 1; cell proliferation-inducing gene 21 protein; guanine nucleotide binding protein beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-like protein 12.3; protein homologous to chicken B complex protein, guanine nucleotide binding;
- Gene ID
- 10399
- UniProt ID
- P63244
- Protein Refseq
- NP_006089
- Function
- SH2 domain binding; ion channel inhibitor activity; protein binding; protein kinase C binding; protein phosphatase binding; protein tyrosine kinase inhibitor activity; receptor binding; receptor tyrosine kinase binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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MSDS
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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