Anti-Human IFNA1 Recombinant Antibody (Sifalimumab) (CAT#: TAB-H62)
Recombinant human antibody to Human IFNA1. Sifalimumab is a human monoclonal antibody designed for the treatment of SLE, dermatomyositis, and polymyositis.
Specific Inquiry
ELISA
Figure 1 Pharmacokinetics (PK) and pharmacodynamics of sifalimumab over time in patients with systemic lupus erythematosus (PK population).
Serum concentrations of sifalimumab. Patients who missed the last 3 doses were excluded from the analysis.
Petri, M., Wallace, D. J., Spindler, A., Chindalore, V., Kalunian, K., Mysler, E., ... & Yao, Y. (2013). Sifalimumab, a human anti–interferon‐α monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose‐escalation study. Arthritis & Rheumatism, 65(4), 1011-1021.
Inhib
Figure 2 Change from baseline in disease activity.
Combined sifalimumab group (n 121) and placebo group (n 40).
Petri, M., Wallace, D. J., Spindler, A., Chindalore, V., Kalunian, K., Mysler, E., ... & Yao, Y. (2013). Sifalimumab, a human anti–interferon‐α monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose‐escalation study. Arthritis & Rheumatism, 65(4), 1011-1021.
Specifications
- Host Species
- human
- Derivation
- human
- Type
- IgG1 - kappa
- Specificity
- IFNA1 (interferon alpha 1, IFN-alpha, IFN alpha 1/13, IFN 13) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
- CAS
- 1006877-41-3
- Generic Name
- sifalimumab
- UNII
- XOY1YA7RMC
- MW
- 146.25 kDa
- Related Disease
- Systemic lupus erythematosus (SLE)
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Applications
- Application Notes
- The IFNA1 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- sifalimumab;1006877-41-3;IFNA1;interferon, alpha 1;interferon alpha-1/13;IFL;IFN;IFN ALPHA;IFN alpha 1b;IFN alphaD;IFNA13;IFNA@;interferon alpha 1b;leIF D;IFN-alpha 1b;IFN-alpha-1/13;interferon-alpha1;interferon alpha-D;IFN-ALPHA;IFN-alphaD;MGC138207;MGC1
- Gene ID
- 3439
- UniProt ID
- P01562
Related Resources
Please refer to Sifalimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Sifalimumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Sifalimumab"
Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Sifalimumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human antibody to Human IFNA1. Sifalimumab is a human monoclonal antibody designed for the treatment of SLE, dermatomyositis, and polymyositis.
See other products for "IFNA1"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-074 | Anti-Human IFN alpha Recombinant Antibody (Rontalizumab) | WB | IgG1 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-747 | Anti-IFNA1 Recombinant Antibody (Faralimomab) | FuncS, IF, Neut, ELISA, FC, IP, IHC | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-960CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone N27) | WB, Neut, ELISA | Mouse IgG1, κ |
| NEUT-961CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone 8U18) | Neut, WB | Mouse IgG1 |
| NEUT-1070CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone F17) | Neut | Mouse IgG1 |
| NEUT-1071CQ | Mouse Anti-IFNA1 Recombinant Antibody (clone K9) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4599 | Rabbit Anti-IFNA1 Recombinant Antibody (clone TH112DS) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0322-YC | Mouse Anti-IFNA1 Recombinant Antibody (HPAB-0322-YC) | Neut, ELISA | Mouse IgG |
| HPAB-0323-YC | Human Anti-IFNA1 Recombinant Antibody (HPAB-0323-YC) | Neut, ELISA | Humanized IgG2 |
| HPAB-0324-YC | Human Anti-IFNA1 Recombinant Antibody (HPAB-0324-YC) | ELISA | Chimeric (mouse/human) IgG |
| HPAB-0325-YC | Human Anti-IFNA1 Recombinant Antibody (clone AIA22) | ELISA, Neut | Human IgG |
| HPAB-0437-CN | Human Anti-IFNA1 Recombinant Antibody (HPAB-0437-CN) | ELISA | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0437-CN-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0437-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0438-CN-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0438-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0439-CN-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0439-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0442-CN-S(P) | Mouse Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0442-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0127-WJ-S(P) | Human Anti-IFNA1 Recombinant Antibody; scFv Fragment (HPAB-0127-WJ-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0436-CN-F(E) | Human Anti-IFNA1 Recombinant Antibody (clone 13H5); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-0437-CN-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0437-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0438-CN-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0438-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0439-CN-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0439-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0442-CN-F(E) | Human Anti-IFNA1 Recombinant Antibody; Fab Fragment (HPAB-0442-CN-F(E)) | ELISA, Block | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-747 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Faralimomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-074 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Rontalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H62 | Afuco™ Anti-IFNA1 ADCC Recombinant Antibody (Sifalimumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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