Recombinant Mouse anti-Human IL1R1 Monoclonal antibody (732229) (CAT#: MOB-0953CT)
Recombinant Mouse monoclonal antibody to Human IL1R1, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1237/1774_H4_18_cr5952945990756_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1237/1774_H4_18_cr5952945990756_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7779/211_A1_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7779/211_A1_3_selected.jpg
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong luminal membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29560/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong luminal membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29560/ihc_selected.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_6_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_8.jpg
Figure 6 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_B_8_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_B_8_5.jpg
Figure 7 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_3.jpg
Figure 8 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_9_4.jpg
Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HSkMC)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115594-IL1R1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115594-IL1R1
Specifications
- Immunogen
- The extracellular domain of the type 1 human IL1 Receptor.
- Host Species
- Mouse
- Specificity
- This antibody partially inhibits (30-50%) binding of one another to IL1 Receptor. It does not block binding of IL1 to receptor and they do not cross react with receptors for human IL2 or IL4
- Species Reactivity
- Human
- Clone
- 732229
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunocytochemistry/Immunofluorescence; RIA
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.1 mg/ml
- Buffer
- Preservative: None Constituents: PBS, pH 7.4
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- IL1R1; interleukin 1 receptor, type I; P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha; interleukin-1 receptor type 1; IL-1R-1; IL-1RT1; IL-1RT-1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor alpha, type I;
- Gene ID
- 3554
- UniProt ID
- P14778
- Protein Refseq
- NP_000868
- Function
- interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity; platelet-derived growth factor receptor binding; protease binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activ
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1421z | Mouse Anti-IL1R1 Recombinant Antibody (clone 32H6) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| HPAB-1862-FY | Human Anti-IL1R1 Recombinant Antibody (clone 26F5) | Inhib, Block | Human IgG1 |
| HPAB-1863-FY | Human Anti-IL1R1 Recombinant Antibody (clone 15C4) | Inhib, Block | Human IgG1 |
| VS3-QX596 | Mouse Anti-IL1R1 Recombinant Antibody (clone D12-D2) | WB, FC, ELISA | Mouse IgG1 |
| VS3-QX597 | Mouse Anti-IL1R1 Recombinant Antibody (clone 4D2D12) | ELISA, FC | Mouse IgG1 |
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