Anti-Human IL5 Recombinant Antibody (TAB-031) (CAT#: TAB-031)
Recombinant monoclonal antibody to Human IL5. It is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5), and is used to treat certain kinds of asthma and white blood cell diseases. Recent studies have concluded that mepolizumab may improve exacerbations in patients with severe eosinophilic asthma, an adult-onset asthma which represents less than 5% of all asthma. IL-5 is a chemical messenger in the immune system that stimulates the growth of eosinophils. In eosinophilic asthma, eosinophils are present in the lungs. When mepolizumab was given to people with eosinophilic asthma, it eliminated eosinophils from the bloodstream,and reduced eosinophils in the lungs and bone marrow.
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SDS-PAGE
Figure 1 Anti-Human IL5 Recombinant Antibody (TAB-031) in SDS-PAGE
Lane 1: Human IgG1, κ Isotype control (5.0 μg) (Reduced)
Lane 2: TAB-031 (5.0 μg) (Reduced)
Lane 3: Human IgG1, κ Isotype control (5.0 μg) (Non-reduced)
Lane 4: TAB-031 (5.0 μg) (Non-reduced)
M: SDS-PAGE Marker
Specifications
- Immunogen
- Recombinant human IL5.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC, ICC
- Related Disease
- Asthma
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The IL5 antibody has been reported in applications of Activ, IHC.
Target
- Alternative Names
- Mepolizumab;bosatria;196078-29-2;SB-240563;IL5;interleukin 5 (colony-stimulating factor, eosinophil);interleukin-5;B cell differentiation factor I;EDF;eosinophil differentiation factor;IL 5;interleukin 5;T cell replacing factor;TRF;T-cell replacing factor
- Gene ID
- 3567
- UniProt ID
- P05113
Related Resources
Please refer to Mepolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Mepolizumab.
Asthma
Inflammatory Bowel Diseases
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-136 | Anti-Human IL5 Recombinant Antibody (TAB-136) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
Customer Reviews and Q&As
Customer Review
Q&As
Jessica Green
Excellent for IL5 Research
Excellent for IL5 Research
The Anti-Human IL5 Therapeutic Antibody (Bosatria) has been excellent for our IL5 studies. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
18.Jun,23
Michael Evans
Effective in Immunoassays
Effective in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for IL5 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
23.Nov,22
Sarah Davis
Consistent and Reliable
Consistent and Reliable
This antibody has proven to be consistent and reliable in our assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for IL5 have been particularly beneficial.
12.May,21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-031, RRID: AB_3111765)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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