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Recombinant Mouse anti-Human IRAK4 Monoclonal antibody (A8A8) (CAT#: MOB-0992CT)

Recombinant Mouse monoclonal antibody to Human IRAK4, expressed in Chinese Hamster Ovary cells(CHO).


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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/if_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, cytosol & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/621_E10_5_selected.jpg
Normal Tissue
Figure 3 IHC staining of human colon
Figure 3 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells and smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/ihc_selected.jpg
Figure 4 IHC staining of human breast
Figure 4 IHC staining of human breast
(Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/ihc_selected.jpg
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_B_8_5.jpg
Figure 6 Pancreas
Figure 6 Pancreas
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_1_3.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/37917_A_7_5.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_6_6.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (U-937)
Figure 9 RNA cell line category: Cell line enhanced (U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198001-IRAK4

Specifications

  • Immunogen
  • Recombinant fragment, corresponding to amino acids 1-130 of Human IRAK4, with 26 kDa tag. AAH13316.
  • Host Species
  • Mouse
  • Species Reactivity
  • Human
  • Clone
  • A8A8
  • Applications
  • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunohistochemistry paraffin embedded sections; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein A purified
  • Format
  • Liquid
  • Concentration
  • 0.5 mg/ml
  • Buffer
  • Preservative: None Constituents: 1X PBS, pH 7.2
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Target

  • Alternative Names
  • IRAK4; interleukin-1 receptor-associated kinase 4; IPD1; REN64; IRAK-4; NY-REN-64; renal carcinoma antigen NY-REN-64;
  • Function
  • ATP binding; interleukin-1 receptor binding; magnesium ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "IRAK4"

Recombinant Antibody

CAT Product Name Application Type
MOB-2079z Mouse Anti-IRAK4 Recombinant Antibody (clone 27A3) WB, ELISA, FC, IHC Mouse IgG1
ZG-0770J Rabbit Anti-IRAK4 Recombinant Antibody (clone 10H4) ELISA, WB, FC Rabbit IgG
VS3-FY761 Recombinant Rabbit Anti-IRAK4 Antibody (clone R01-1B2) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG

Mouse Antibody

CAT Product Name Application Type
TAB-0587CL-S(P) Mouse Anti-IRAK4 Recombinant Antibody; scFv Fragment (TAB-0587CL-S(P)) ELISA Mouse scFv
TAB-0587CL-F(E) Mouse Anti-IRAK4 Recombinant Antibody; Fab Fragment (TAB-0587CL-F(E)) ELISA Mouse Fab

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1852 Hi-Affi™ Recombinant Rabbit Anti-IRAK4 Monoclonal Antibody (DS1852AB) ICC, WB IgG
MOR-4632 Hi-Affi™ Recombinant Rabbit Anti-IRAK4 Monoclonal Antibody (TH145DS) WB, IF, ICC, IHC-P, FC, ChIP IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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