Anti-Human KLRC1 Recombinant Antibody (TAB-437CQ) (CAT#: TAB-437CQ)

Recombinant monoclonal antibody to KLRC1. This antibody is a humanized monoclonal antibody that specifically targets NKG2A, a receptor found on the surface of certain immune cells, including NK cells, cytotoxic T lymphocytes (CTLs), and NKT cells.

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ELISA

Figure 1 Anti-Human KLRC1 Recombinant Antibody (Monalizumab) in ELISA.

Figure 1 Anti-Human KLRC1 Recombinant Antibody (Monalizumab) in ELISA.

ELISA analysis of TAB-437CQ was performed by coating with Recombinant Human KLRC1 Protein. Then blocked with BSA, and incubated with Anti-Human KLRC1 Therapeutic Antibody (Monalizumab) (TAB-437CQ). The HRP-conjugated goat anti-human IgG as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.

SDS-PAGE

Figure 2 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in SDS-PAGE

Figure 2 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in SDS-PAGE

SDS-PAGE analysis of TAB-437CQ-FcS-N in non-reduced (Lane 2) and reduced (Lane 1) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.

SEC-HPLC

Figure 3 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in SEC-HPLC

Figure 3 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in SEC-HPLC

HPLC analysis of TAB-437CQ-FcS shows that the purity is 100%.

ELISA

Figure 4 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in ELISA

Figure 4 Anti-Human KLRC1 Recombinant Antibody (Monalizumab, Fc Silenced) in ELISA

ELISA analysis of TAB-437CQ-FcS-N was performed by coating with Human KLRC1 Protein (Arg100-Leu233), His tag.

The secondary antibody: HRP Anti-Human IgG (H+L)


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • IgG4, κ
  • Specificity
  • Human KLRC1
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
  • Conjugate
  • Unconjugated
  • Related Disease
  • Head and neck cancer

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • NKG2; NKG2A; CD159A

Related Resources

  • Biosimilar Overview
  • Citations
Please refer to Monalizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Monalizumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Customer Reviews and Q&As

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  • Great for Immune Studies
    The Monalizumab has been a fantastic addition to our immune cell studies. Its specificity and sensitivity are outstanding, consistently providing clear results. This antibody has become essential for our research, improving the accuracy and reliability of our assays.
  • Effective in Flow Cytometry
    We incorporated this antibody into our flow cytometry experiments, and it's been a great asset. The specificity for target cells is precise, allowing for accurate cell population analysis. The reliable performance has made it an invaluable tool in our lab.
  • Consistent and Reliable
    This antibody has proven to be consistent and reliable in our immunoassays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for its target have been particularly beneficial.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-437CQ, RRID: AB_3111944)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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