Recombinant Mouse anti-Human MLL Monoclonal antibody (20G9E8) (CAT#: MOB-1038CT)
Recombinant Mouse monoclonal antibody to Human MLL, expressed in Chinese Hamster Ovary cells(CHO).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/44910/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/44910/if_selected.jpg
Figure 2 Cerebellum.
(High expression in cerebellum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17794/42699_B_9_8_val_selected.jpg
(High expression in cerebellum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17794/42699_B_9_8_val_selected.jpg
Figure 3 Testis
(Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_6_6.jpg
(Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_6_6.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_8.jpg
Figure 5 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_B_8_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_B_8_5.jpg
Figure 6 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_3.jpg
Figure 7 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24270/146580_A_8_5.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118058-KMT2A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118058-KMT2A
Specifications
- Immunogen
- Purified truncated recombinant MLL-Trx(aa3751-3968) which is expressed in E.Coli strain BL21 (DE3).
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 20G9E8
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Ascites
- Format
- Liquid
- Buffer
- Preservative: None Constituents: Ascites
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
- Alternative Names
- KMT2A; lysine (K)-specific methyltransferase 2A; HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; MLL/GAS7; TET1-MLL; histone-lysine N-methyltransferase 2A; trithorax-like protein; CDK6/MLL fusion protein; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; zinc finger protein HRX; mixed lineage leukemia 1; lysine N-methyltransferase 2A; MLL-AF4 der(11) fusion protein; CXXC-type zinc finger protein 7; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);
- Gene ID
- 4297
- UniProt ID
- Q03164
- Protein Refseq
- NP_001184033
- Function
- AT DNA binding; DNA binding; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase activity (H3-K4 specific); identical protein binding; metal ion binding; methyltransferase activity; protein binding
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3092z | Mouse Anti-KMT2A Recombinant Antibody (clone 11B11) | WB, ELISA, IHC | Mouse IgG1 |
| ZG-0285C | Mouse Anti-KMT2A Recombinant Antibody (ZG-0285C) | WB, IHC, ELISA | Mouse IgG |
| VS3-XY991 | Mouse Anti-KMT2A Recombinant Antibody (clone 10F8D7) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-FY800 | Recombinant Mouse Anti-KMT2A Antibody (clone 7E1D10) | ELISA, IHC, ICC, FC | Mouse IgG1 |
| VS7-0425-WR393 | Mouse Anti-KMT2A Monoclonal Antibody (clone 10F8D7) | IHC | Mouse IgG1 |
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