Recombinant Mouse anti-Human NR1H3 Monoclonal antibody (FQS3403)
CAT#: MOB-2318CT
Recombinant Mouse Monoclonall antibody to Human NR1H3, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36443/1050_C11_2_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37109/94492_A_8_8.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37109/94492_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37109/94492_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37109/94492_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37109/94492_A_1_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC TERT1, HSkMC)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000025434-NR1H3
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Specifications
- Immunogen
- E.coli-expressed recombinant fragment, corresponding to amino acids 164-447 of Human LXR alpha.
- Host Species
- Mouse
- Specificity
- Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
- Species Reactivity
- Human
- Clone
- FQS3403
- Applications
- Used for immunoassay techniques such as: ChImmunoprecipitation; Western Blot; Enzyme-linked Immunosorbent Assay; Immunoprecipitation; GSA; Immunohistochemistry paraffin embedded sections; Flow Cytometry
- Conjugate
- Unconjugated
Product Property
- Format
- Liquid
- Buffer
- Physiological saline. Preservative: 0.1% Sodium Azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- NR1H3; nuclear receptor subfamily 1, group H, member 3; LXRA; LXR-a; RLD-1; oxysterols receptor LXR-alpha; liver X nuclear receptor alpha variant 1;
- Gene ID
- 10062
- UniProt ID
- Q13133
- Protein Refseq
- NP_001123573
- Function
- DNA binding; cholesterol binding; ligand-dependent nuclear receptor activity; metal ion binding; protein binding; protein heterodimerization activity; receptor activity; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA bin
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| MOR-2488 | Hi-Affi™ Recombinant Rabbit Anti-NR1H3 Monoclonal Antibody (DS2488AB) | FC, WB, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
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| MRO-0946-CN | Recombinant Rabbit Anti-NR1H3 Monoclonal Antibody (JA20-38) | WB, IF, IHC, FC | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC837 | CytoStream™ Rabbit Anti-NR1H3 Recombinant Antibody (VS13-YC837) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0325-XY1512 | Anti-NR1H3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4943 | Anti-Mouse NR1H3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4942 | Anti-Human NR1H3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4944 | Anti-Rat NR1H3 Immunohistochemistry Kit | IHC |
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