Anti-Human NRP1 Recombinant Antibody (Vesencumab) (CAT#: TAB-264)
Recombinant monoclonal antibody to NRP1. Vesencumab is an immunomodulator designed for the treatment of solid malignancies. It binds to neuropilin 1.
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DB
Figure 1 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in DB
Dot Blot analysis of TAB-264 was performed by coating with human NRP1 protein (His tag).
TAB-264 incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-Human IgG was used as a secondary antibody (1: 6000)
WB
Figure 2 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in WB
Western blot analysis of TAB-264 was performed with human NRP1 protein onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-264 and HRP goat anti-Human IgG was used as a secondary antibody (1: 6000). Chemiluminescent detection was performed.
Lane 1: Reduced antigen (0.1 μg)
Lane 2: Reduced antigen (0.3 μg)
Lane 3: Reduced antigen (0.6 μg)
ELISA
Figure 3 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in ELISA
ELISA analysis of TAB-264 was performed by coating with human NRP1 protein (His tag). Then blocked with BSA and incubated with TAB-264. The HRP-conjugated goat anti-Human IgG was used as a secondary antibody (1: 6000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in WB, FuncS, IF, Neut, ELISA, FC, IP and most other immunological methods.
- CAS
- 1205533-60-3
- Generic Name
- Vesencumab
- MW
- 145.0 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- Vesencumab;1205533-60-3;Genentech Anti-NRP1;RG7347;MNRP1685A;NRP1;neuropilin 1;neuropilin-1;CD304;NRP;VEGF165R;transmembrane receptor;vascular endothelial cell growth factor 165 receptor;NP1;BDCA4;DKFZp781F1414;DKFZp686A03134;
- Gene ID
- 8829
- UniProt ID
- O14786
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Vesencumab"
Afuco™ Anti-NRP1 ADCC Recombinant Antibody (Vesencumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to NRP1. Vesencumab is an immunomodulator designed for the treatment of solid malignancies. It binds to neuropilin 1.
See other products for "NRP1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1428z | Mouse Anti-NRP1 Recombinant Antibody (clone 25G6) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MOR-2483 | Hi-Affi™ Recombinant Rabbit Anti-NRP1 Monoclonal Antibody (DS2483AB) | WB, FC, IP, IHC | IgG |
| HPAB-0514-CN | Human Anti-NRP1 Recombinant Antibody (HPAB-0514-CN) | ELISA, FC, Block | Human IgG1 |
| HPAB-0515-CN | Human Anti-NRP1 Recombinant Antibody (HPAB-0515-CN) | ELISA, FC, Block | Human IgG1 |
| VS3-XY1185 | Mouse Anti-NRP1 Recombinant Antibody (clone 5D8) | ELISA, WB, FC | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-095 | Human Anti-NRP1 Recombinant Antibody; scFv Fragment | Block | Human scFv |
| HPAB-0514-CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-0514-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0515-CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-0515-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-N0370-YC-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-N0370-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-1797-FY-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-1797-FY-F(E)) | FC, ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-589MZ-S(P) | Rabbit Anti-NRP1 Recombinant Antibody; scFv Fragment (TAB-589MZ-S(P)) | IHC | Rabbit scFv |
| TAB-590MZ-S(P) | Anti-Human NRP1 Recombinant Antibody scFv Fragment (1.004.012) | WB, IHC | |
| TAB-591MZ-S(P) | Anti-Human NRP1 Recombinant Antibody scFv Fragment | FC, IP | |
| TAB-589MZ-F(E) | Rabbit Anti-NRP1 Recombinant Antibody; Fab Fragment (TAB-589MZ-F(E)) | IHC | Rabbit Fab |
| TAB-590MZ-F(E) | Anti-Human NRP1 Recombinant Antibody Fab Fragment (1.004.012) | WB, IHC |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1791CQ | Recombinant Rat Anti-Nrp1 Antibody (CBL881) | FC, Neut | IgG2 |
| NEUT-1793CQ | Recombinant Rat Anti-Nrp1 Antibody (CBL384) | CyTOF, FC, Neut | IgG2a |
| NEUT-1794CQ | Recombinant Mouse Anti-Nrp1 Antibody (CBL326) | BL, FC, CyTOF | IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2501 | Hi-Affi™ Recombinant Rabbit Anti-NRP1 Monoclonal Antibody (DS2501AB) | WB, IHC-P, IP, FC, IHC-Fr | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0514-CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-0514-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0515-CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-0515-CN-F(E)) | ELISA, FC, Block | Human Fab |
| NS-056CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-056CN-F(E)) | ELISA, IP, IF | Human Fab |
| NS-057CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-057CN-F(E)) | ELISA, IP, IF | Human Fab |
| HPAB-1357-FY-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-1357-FY-S(P)) | Block, Inhib | Human scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-055CN | Human Anti-NRP1 Recombinant Antibody (NS-055CN) | ELISA, IP, IF, SPR | Human IgG |
| NS-056CN | Human Anti-NRP1 Recombinant Antibody (NS-056CN) | ELISA, IP, IF, SPR | Human IgG |
| NS-057CN | Human Anti-NRP1 Recombinant Antibody (NS-057CN) | ELISA, IP, IF, SPR | Human IgG |
| NS-055CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-055CN-F(E)) | ELISA, IP, IF | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-264 | Afuco™ Anti-NRP1 ADCC Recombinant Antibody (Vesencumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1093 | PE-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
| MHC-CN1094 | APC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
| MHC-CN1095 | FITC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
| MHC-CN1096 | A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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