Recombinant Mouse anti-Human PAK3 Monoclonal antibody (EML2324) (CAT#: MOB-1537CT)
Recombinant Mouse monoclonal antibody to Human PAK3, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HAP1
(Immunofluorescent staining of human cell line HAP1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44791/1918_E6_28_cr5cb48efe99beb_selected.jpg
(Immunofluorescent staining of human cell line HAP1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44791/1918_E6_28_cr5cb48efe99beb_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Not detected Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_B_7_5.jpg
(Glial cells Staining: Not detected Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_B_7_5.jpg
Figure 4 Cerebellum
(Purkinje cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_B_9_8.jpg
(Purkinje cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_B_9_8.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60219/142917_A_8_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (EFO-21, HAP1, HDLM-2, NTERA-2, SCLC-21H, SH-SY5Y, U-2197, U-251 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000077264-PAK3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000077264-PAK3
Specifications
- Immunogen
- Recombinant fragment: MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS IFPGGGDKTN KKKEKERPEI SLPSDFEHTI HVGFDAVTGE , corresponding to amino acids 1-90 of Human PAK3
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML2324
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PAK3; p21 protein (Cdc42/Rac)-activated kinase 3; bPAK; MRX30; MRX47; OPHN3; hPAK3; CDKN1A; PAK3beta; serine/threonine-protein kinase PAK 3; PAK-3; beta-PAK; oligophrenin-3; p21-activated kinase 3; p21 (CDKN1A)-activated kinase 3;
- Gene ID
- 5063
- UniProt ID
- O75914
- Protein Refseq
- NP_001121638
- Function
- ATP binding; MAP kinase kinase activity; SH3 domain binding; metal ion binding; nucleotide binding; protein serine/threonine kinase activity;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2584 | Hi-Affi™ Recombinant Rabbit Anti-PAK3 Monoclonal Antibody (DS2584AB) | WB, IP, IHC | IgG |
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