Recombinant Mouse anti-Human PDE2A Monoclonal antibody (EML598)
CAT#: MOB-1326CT
Recombinant Mouse monoclonal antibody to Human PDE2A, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9752/1020_G2_4_selected.jpg
Normal Tissue
Figure 2 Spleen
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31192/144618_B_7_4_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows distinct nuclear and cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9752/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9752/32523_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31192/144618_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31192/144618_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (HeLa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186642-PDE2A
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Specifications
- Immunogen
- Recombinant fragment: REKAYIPELQ ISFMEHIAMP IYKLLQDLFP KAAELYERVA SNREHWTKVS HKFTIRGLPS NNSLDFLDEE YEVPDLDGTR APINGCCSLD A, corresponding to amino acids 850-941 of Human PDE2A
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML598
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.5 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PDE2A; phosphodiesterase 2A, cGMP-stimulated; PDE2A1; PED2A4; cGSPDE; CGS-PDE; cGMP-dependent 3,5-cyclic phosphodiesterase; cGMP-stimulated phosphodiesterase 1; cGMP-stimulated phosphodiesterase 4; cyclic GMP-stimulated phosphodiesterase;
- Gene ID
- 5138
- UniProt ID
- O00408
- Protein Refseq
- NP_001137311
- Function
- 3,5-cyclic-nucleotide phosphodiesterase activity; TPR domain binding; cAMP binding; cGMP binding; cGMP binding; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; calcium channel activity; cyclic-nucleotide phosphodiesterase activity; drug bind
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Related Signaling Pathways
cAMP Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PDE2A"
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| CAT | Product Name | Application | Type |
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| MOR-2629 | Hi-Affi™ Recombinant Rabbit Anti-PDE2A Monoclonal Antibody (DS2629AB) | WB | IgG |
| CAT | Product Name | Application | Type |
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| VS4-CJ69 | Recombinant Rabbit Anti-PDE2A Antibody (clone 11C6) | ELISA, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0525-XY5266 | Anti-PDE2A Immunohistochemistry Kit | IHC |
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