Anti-Human RON Recombinant Antibody (Narnatumab)
CAT#: TAB-184
Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/44_E6_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_1.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164078-MST1R
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Specifications
- Immunogen
- RE7 cells and MDCK cells overexpressing the human RON receptor in complete Freund`s adjuvant
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
- CAS
- 1188275-92-4
- Generic Name
- Narnatumab
- MW
- 145.9 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Narnatumab;1188275-92-4;IMC-RON8;MST1R;macrophage stimulating 1 receptor (c-met-related tyrosine kinase);PTK8, PTK8 protein tyrosine kinase 8 , RON;macrophage-stimulating protein receptor;CD136;CDw136;p185-Ron;MSP receptor;RON variant E2E3;MST1R variant R
- Gene ID
- 4486
- UniProt ID
- Q04912
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Narnatumab"
Afuco™ Anti-MST1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-184)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to RON. It is a human monoclonal antibody designed for the treatment of cancer.
See other products for "MST1R"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3123z | Mouse Anti-MST1R Recombinant Antibody (clone 29B12) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-687-FY | Mouse Anti-MST1R Recombinant Antibody (clone 07F01) | Neut, Inhib, Cyt, ELISA | Mouse IgG |
| HPAB-688-FY | Mouse Anti-MST1R Recombinant Antibody (clone 29B06) | Neut, Inhib, ELISA | Mouse IgG |
| HPAB-689-FY | Mouse Anti-MST1R Recombinant Antibody (clone 18H09) | Neut, Inhib | Mouse IgG |
| VS7-0425-WR429 | Mouse Anti-MST1R Monoclonal Antibody (VS7-0425-WR429) | WB, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-332CT | Anti-Human RON Recombinant Antibody (TAB-332CT) | WB, ELISA, FC | Human antibody |
| TAB-333CT | Human Anti-MST1R Recombinant Antibody (TAB-333CT) | WB, ELISA, FC, IP | Human IgG |
| TAB-332CT-S(P) | Anti-Human RON Recombinant Antibody scFv Fragment (TAB-332CT-S(P)) | WB, ELISA, FC | Human antibody |
| TAB-332CT-F(E) | Anti-Human RON Recombinant Antibody Fab Fragment (TAB-332CT-F(E)) | WB, ELISA, FC | Human antibody |
| TAB-333CT-F(E) | Human Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-333CT-F(E)) | WB, ELISA, FC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-331CT-S(P) | Anti-Human RON Recombinant Antibody scFv Fragment (TAB-331CT-S(P)) | WB, ELISA, FC | |
| TAB-334CT-S(P) | Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-334CT-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| TAB-335CT-S(P) | Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-335CT-S(P)) | WB, ELISA, FC, IP | Mouse scFv |
| TAB-331CT-F(E) | Anti-Human RON Recombinant Antibody Fab Fragment (TAB-331CT-F(E)) | WB, ELISA, FC | |
| TAB-334CT-F(E) | Mouse Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-334CT-F(E)) | WB, ELISA, FC, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1756CQ | Recombinant Mouse Anti-MST1R Antibody (CBL312) | BL | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1757CQ | Recombinant Mouse Anti-MST1R Antibody (MM0478-10F24) | Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2309 | Hi-Affi™ Recombinant Rabbit Anti-MST1R Monoclonal Antibody (DS2309AB) | FC, ICC, IF, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0821-CN-F(E) | Human Anti-MST1R Recombinant Antibody (clone MOR07692); Fab Fragment | WB, ELISA, FC | Human Fab |
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| HPAB-J0189-YC-F(E) | Mouse Anti-MST1R Recombinant Antibody (clone 17F06); Fab Fragment | ELISA, Neut, FuncS | Mouse Fab |
| HPAB-J0190-YC-F(E) | Human Anti-MST1R Recombinant Antibody (clone Ch07F01 C102S); Fab Fragment | ELISA, Neut, FuncS | Chimeric (mouse/human) Fab |
| HPAB-J0191-YC-F(E) | Human Anti-MST1R Recombinant Antibody (clone Sh07F01 Hv3-48); Fab Fragment | ELISA, Neut, FuncS | Humanized (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-687-FY-S(P) | Mouse Anti-MST1R Recombinant Antibody (clone 07F01); scFv Fragment | Inhib, ELISA, FC | Mouse scFv |
| HPAB-688-FY-S(P) | Mouse Anti-MST1R Recombinant Antibody (clone 29B06); scFv Fragment | Inhib, ELISA, FC | Mouse scFv |
| HPAB-689-FY-S(P) | Mouse Anti-MST1R Recombinant Antibody (clone 18H09); scFv Fragment | Inhib, ELISA, FC | Mouse scFv |
| HPAB-690-FY-S(P) | Mouse Anti-MST1R Recombinant Antibody (clone Sh07F01-2); scFv Fragment | Block | Mouse scFv |
| HPAB-1589-FY-F(E) | Mouse Anti-MST1R Recombinant Antibody Fab Fragment (HPAB-1589-FY-F(E)) | WB, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-184 | Afuco™ Anti-MST1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-184) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY190 | AbPlus™ Anti-MST1R Magnetic Beads (MOR07923) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY152 | Human Anti-MST1R (clone M93-D02) scFv-Fc Chimera | WB, ELISA, FC, IP | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC486 | Recombinant Anti-MST1R Vesicular Antibody, EV Displayed (VS-0425-YC486) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4549 | Anti-MST1R Immunohistochemistry Kit | IHC |
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