Recombinant Mouse anti-Human TGFBR3 Monoclonal antibody (NN0068-6H0)
CAT#: MOB-2023CT
Recombinant Mouse monoclonal antibody to Human TGFBR3, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows distinct membranous positivity in cells in glomeruli.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_6_6.jpg
Normal Tissue
Figure 7 Ovary
Ovarian stroma cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_5_7.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, RT4, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000069702-TGFBR3/subcellular
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Specifications
- Immunogen
- Recombinant human TGF beta Receptor III extracellular domain
- Host Species
- Mouse
- Specificity
- This antibody was selected for its ability to detect TGF beta Receptor III. No cross reactivity was found to TGF beta Receptor I and Receptor II.
- Species Reactivity
- Human
- Clone
- NN0068-6H0
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.2 mg/ml
- Buffer
- Preservative: None Constituents: PBS
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- TGFBR3; transforming growth factor, beta receptor III; BGCAN; betaglycan; transforming growth factor beta receptor type 3; TGFR-3; betaglycan proteoglycan; TGF-beta receptor type 3; TGF-beta receptor type III;
- Gene ID
- 7049
- UniProt ID
- Q03167
- Protein Refseq
- NP_001182612
- Function
- PDZ domain binding; SMAD binding; coreceptor activity; glycosaminoglycan binding; glycosaminoglycan binding; heparin binding; protein binding; contributes_to protein binding; receptor activity; transforming growth factor beta binding; transforming growth
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Related Signaling Pathways
TGF-β Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
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