Recombinant Human Anti-IAV HA Antibody (100F4) (CAT#: PABL-584)
Recombinant Human Antibody (100F4) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Neut
Figure 1 Neutralization activity of 7 monoclonal antibodies against H5N1 SZ06 and H5N8 NE14 pseudotypes using PN assay.
The titration of neutralization activity of antibody 100F4 against H5N1 SZ06 (green color line) and H5N8 NE14 (red color line) pseudotypes, respectively.
Ren, H., Wang, G., Wang, S., Chen, H., Chen, Z., Hu, H., ... & Zhou, P. (2016, August). Cross-protection of newly emerging HPAI H5 viruses by neutralizing human monoclonal antibodies: a viable alternative to oseltamivir. In MAbs (Vol. 8, No. 6, pp. 1156-1166). Taylor & Francis.
FuncS
Figure 2 In vivo efficacy of antibody 100F4 against the H5N8 NE14 virus.
Prophylactic efficacy of antibody 100F4. Time course of body weight changes.
Ren, H., Wang, G., Wang, S., Chen, H., Chen, Z., Hu, H., ... & Zhou, P. (2016, August). Cross-protection of newly emerging HPAI H5 viruses by neutralizing human monoclonal antibodies: a viable alternative to oseltamivir. In MAbs (Vol. 8, No. 6, pp. 1156-1166). Taylor & Francis.
Specifications
- Immunogen
- IAV haemagglutinin
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native IAV HA
- Species Reactivity
- IAV
- Clone
- 100F4
- Applications
- Neut, FuncS
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Neutralization and Function Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 100F4"
See other products for "IAV HA"
Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products
Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
Epitope-Specific Antibody Products
Fab Antibody Products
ADCC Enhanced Antibody Products
MHC Tetramer Products for Virology
IgM Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-078 | Recombinant Anti-IAV HA VHH Single Domain Antibody | FC, CA, IP, FuncS | Llama VHH |
| HPAB-0344CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0344CQ) | ELISA, Neut | Llama VHH |
| HPAB-0345CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0345CQ) | ELISA, Neut | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABL-584. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: ELISA
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
