Recombinant Mouse Antibody (CA7) is capable of binding to ICAM-1, expressed in Chinese Hamster Ovary cells (CHO). CA7 antibody binds to monomeric but not dimeric ICAM-1.
Figure 1 ELISA
Purified ICAM-1 prepa- ons (500 ng/ml) were tested for binding to immobilized R6.5, CA7, or 2H 11 b. Bound ICAM-1 was detected with biotin-conjugated-CBRIC1/11 mAb owed by streptavidin-conjugated horseradish peroxidase
Jun, C. D., Shimaoka, M., Carman, C. V., Takagi, J., & Springer, T. A. (2001). Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion. Proceedings of the National Academy of Sciences, 98(12), 6830-6835.
Figure 2 Differential ICAM-1 epitope expression on normal cells and ICAM-1 transfected cells.
Binding of mouse mAbs TS2/18 (negative control, solid) RR1/1 (dotted), CA7 (stippled), and M261PP5C7 (dashed) was determined by subsequent binding of FITC goat anti-mouse IgG and flow microfluorimetry on a FACSan® (Becton Dickinson and Co.). Cells tested were (A) JY B lymphoblasts; (B) BHK-VP16 cells transfected with transmembrane ICAM-1; and (C) BHK-VP16 cells transfected with GPI-ICAM-1.
Miller, J., Knorr, R., Ferrone, M., Houdei, R., Carron, C. P., & Dustin, M. L. (1995). Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1. Journal of Experimental Medicine, 182(5), 1231-1241.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1937-VHH | Recombinant Anti-human ICAM1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
TAB-126CT | Llama Anti-ICAM1 Recombinant Antibody (TAB-126CT) | ELISA, IF | Llama VHH |
HPAB-0349-YC-VHH | Recombinant Llama Anti-ICAM1 Single Domain Antibody (34-1) | ELISA | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-241 | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (Enlimomab Pegol) | WB, IF, IP, Neut, FuncS, ELISA, FC | Fab' - G2a |
TAB-H26 | Anti-Human ICAM1 Recombinant Antibody (Enlimomab) | Neut, ELISA, IF, IP, FuncS, FC, WB | IgG2a |
TAB-124CT | Anti-Human ICAM-1 Recombinant Antibody (m1A6) | ELISA | |
TAB-124CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (m1A6) | ELISA | |
TAB-124CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (m1A6) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L023R | anti-ICAM1 immunotoxin UV3 (IgG)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-121CT | Anti-Human ICAM-1 Recombinant Antibody (MD-2) | ELISA, FC | Human antibody |
TAB-125CT | Anti-Human ICAM-1 Recombinant Antibody (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
TAB-121CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (MD-2) | ELISA, FC | Human antibody |
TAB-122CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (R6-5-D6) | ELISA, FC | Human antibody |
TAB-125CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-123CT | Anti-Human ICAM-1 Recombinant Antibody (h1A6) | ELISA | Humanized antibody |
TAB-123CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (h1A6) | ELISA | Humanized antibody |
TAB-123CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (h1A6) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-104LC | Recombinant Anti-Human ICAM1 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-923CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone CBL236) | Neut, IF, FC, WB, IHC | Mouse IgG1 |
NEUT-925CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone HA58) | FC, FuncS, IHC, Neut, WB | Mouse IgG1, κ |
NEUT-926CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC182) | FC, IF, IHC, ICC, Neut | Mouse IgG2b |
NEUT-927CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone RR1/1) | FC, IF, IHC, Neut, WB, ELISA | Mouse IgG1 |
NEUT-930CQ | Rat Anti-Icam1 Recombinant Antibody (clone KAT1) | FC, FuncS, IHC-Fr, Neut, IP | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-924CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone HCD54) | FC, IF, Block | Mouse IgG1, κ |
NEUT-928CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC183) | Block, FC, IHC, IP | Mouse IgG1 |
NEUT-929CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone BBIG-I1(11C81)) | Block, WB, IP, ICC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1723 | Rabbit Anti-ICAM1 Recombinant Antibody (clone DS1723AB), Biotin | IHC-Fr, IP, WB, ELISA | Rabbit IgG |
MOR-1724 | Rabbit Anti-Icam1 Recombinant Antibody (clone DS1724AB) | ELISA | Rabbit IgG |
MOR-4598 | Rabbit Anti-ICAM1 Recombinant Antibody (clone TH111DS) | WB, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-1635LC | Mouse Anti-ICAM1 Recombinant Antibody (clone c78.4A) | FC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0043-FY | Human Anti-ICAM1 Recombinant Antibody (clone Icmo0191) | ELISA | Human IgG1, λ |
MRO-0805-CN | Mouse Anti-ICAM1 Recombinant Antibody (clone F11-A4) | WB, IF, IHC | Mouse IgG1a |
MRO-0806-CN | Mouse Anti-ICAM1 Recombinant Antibody (clone J0-F7) | WB, IF, IHC, FC | Mouse IgG2a |
MRO-0807-CN | Rabbit Anti-ICAM1 Recombinant Antibody (clone CBACN-298) | WB, IF, IHC | Rabbit IgG |
MRO-1952-CN | Rabbit Anti-ICAM1 Polyclonal Antibody (MRO-1952-CN) | WB, IF, IHC, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0859-CN-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone BI-AB); scFv Fragment | ELISA, FC, Neut | Human scFv |
HPAB-662-FY-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone ICM10088); scFv Fragment | Inhib | Human scFv |
HPAB-S0064-YC-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone HumD); scFv Fragment | ELISA, FuncS | Humanized scFv |
HPAB-S0065-YC-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone HumF); scFv Fragment | ELISA, FuncS | Humanized scFv |
HPAB-S0066-YC-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone HumH); scFv Fragment | ELISA, FuncS | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0859-CN-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone BI-AB); Fab Fragment | ELISA, FC, Neut | Human Fab |
HPAB-662-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone ICM10088); Fab Fragment | Inhib | Human Fab |
HPAB-S0062-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumB); Fab Fragment | ELISA, FuncS | Humanized Fab |
HPAB-S0063-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumC); Fab Fragment | ELISA, FuncS | Humanized Fab |
HPAB-S0064-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumD); Fab Fragment | ELISA, FuncS | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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