Human Anti-ICAM1 Recombinant Antibody (clone B11) (CAT#: HPAB-0053-YC)
The antibody molecules selectively binds to a cell surface antigen of a target cell, and induce apoptosis of the target cell. It can be uesd to for apoptosis induction.
Specific Inquiry
IHC
Figure 1 Immunohistochemical quantitation of F4/80+ macrophages in tumor tissue.
Tumors treated with control antibody or BI-505. Graphs show mean F4/80+ and NK-cellpositive tumor areas, respectively.
Veitonmäki, N., Hansson, M., Zhan, F., Sundberg, A., Löfstedt, T., Ljungars, A., ... & Danielsson, L. (2013). A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo. Cancer cell, 23(4), 502-515.
Inhib
Figure 2 Dose-Dependent Antitumor Activity Correlates with ICAM-1 Receptor Occupancy on Tumor Cell Surfaces.
There were eight to ten animals per treatment group.
Veitonmäki, N., Hansson, M., Zhan, F., Sundberg, A., Löfstedt, T., Ljungars, A., ... & Danielsson, L. (2013). A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo. Cancer cell, 23(4), 502-515.
FC
Figure 3 FACS analysis of BI-505 and rituximab epitopes on the surface of ARH-77.
Antibodies were used at binding saturating concentrations.
Veitonmäki, N., Hansson, M., Zhan, F., Sundberg, A., Löfstedt, T., Ljungars, A., ... & Danielsson, L. (2013). A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo. Cancer cell, 23(4), 502-515.
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG1
- Specificity
- Human ICAM1
- Species Reactivity
- Human
- Clone
- B11
- Applications
- Inhib, FC, IHC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The ICAM1 antibody has been reported in applications of Flow Cytometry, Inhibition, Immunohistochemistry.
Target
Related Resources
Rheumatoid Arthritis
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TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone B11"
See other products for "ICAM1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1937-VHH | Recombinant Anti-human ICAM1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| TAB-126CT | Llama Anti-ICAM1 Recombinant Antibody (TAB-126CT) | ELISA, IF | Llama VHH |
| HPAB-0349-YC-VHH | Recombinant Llama Anti-ICAM1 Single Domain Antibody (34-1) | ELISA | Llama VHH |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241 | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (Enlimomab Pegol) | WB, IF, IP, Neut, FuncS, ELISA, FC | Fab' - G2a |
| TAB-H26 | Anti-Human ICAM1 Recombinant Antibody (Enlimomab) | Neut, ELISA, IF, IP, FuncS, FC, WB | IgG2a |
| TAB-124CT | Anti-Human ICAM-1 Recombinant Antibody (m1A6) | ELISA | |
| TAB-124CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (m1A6) | ELISA | |
| TAB-124CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (m1A6) | ELISA |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L023R | anti-ICAM1 immunotoxin UV3 (IgG)-RTA | Cytotoxicity assay, Functional assay |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-121CT | Anti-Human ICAM-1 Recombinant Antibody (MD-2) | ELISA, FC | Human antibody |
| TAB-122CT | Anti-Human ICAM-1 Recombinant Antibody (R6-5-D6) | ELISA, FC | Human antibody |
| TAB-125CT | Anti-Human ICAM-1 Recombinant Antibody (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
| TAB-125CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
| TAB-125CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (ICM 10064) | Inhibit, ELISA, WB | Human antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-123CT | Anti-Human ICAM-1 Recombinant Antibody (h1A6) | ELISA | Humanized antibody |
| TAB-123CT-S(P) | Anti-Human ICAM-1 Recombinant Antibody scFv Fragment (h1A6) | ELISA | Humanized antibody |
| TAB-123CT-F(E) | Anti-Human ICAM-1 Recombinant Antibody Fab Fragment (h1A6) | ELISA | Humanized antibody |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-104LC | Recombinant Anti-Human ICAM1 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-923CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone CBL236) | Neut, IF, FC, WB, IHC | Mouse IgG1 |
| NEUT-925CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone HA58) | FC, FuncS, IHC, Neut, WB | Mouse IgG1, κ |
| NEUT-926CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC182) | FC, IF, IHC, ICC, Neut | Mouse IgG2b |
| NEUT-927CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone RR1/1) | FC, IF, IHC, Neut, WB, ELISA | Mouse IgG1 |
| NEUT-933CQ | Mouse Anti-Icam1 Recombinant Antibody (clone 1A29) | WB, IP, ICC, IF, IHC-P, Neut, FC | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-924CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone HCD54) | FC, IF, Block | Mouse IgG1, κ |
| NEUT-928CQ | Mouse Anti-ICAM1 Recombinant Antibody (VMC183) | Block, FC, IHC, IP | Mouse IgG1 |
| NEUT-929CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone BBIG-I1(11C81)) | Block, WB, IP, ICC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1723 | Rabbit Anti-ICAM1 Recombinant Antibody (clone DS1723AB), Biotin | IHC-Fr, IP, WB, ELISA | Rabbit IgG |
| MOR-1724 | Rabbit Anti-Icam1 Recombinant Antibody (clone DS1724AB) | ELISA | Rabbit IgG |
| MOR-4598 | Rabbit Anti-ICAM1 Recombinant Antibody (clone TH111DS) | WB, FC | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-1635LC | Mouse Anti-ICAM1 Recombinant Antibody (clone c78.4A) | FC | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-662-FY-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone ICM10088); scFv Fragment | Inhib | Human scFv |
| HPAB-1728-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC1555); scFv Fragment | ELISA | Human scFv |
| HPAB-1729-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC3040); scFv Fragment | ELISA | Human scFv |
| HPAB-1730-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone LAC3041); scFv Fragment | ELISA | Human scFv |
| HPAB-S0066-YC-S(P) | Human Anti-ICAM1 Recombinant Antibody (clone HumH); scFv Fragment | ELISA, FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-662-FY-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone ICM10088); Fab Fragment | Inhib | Human Fab |
| HPAB-S0062-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumB); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-S0063-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumC); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-S0064-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumD); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-S0065-YC-F(E) | Human Anti-ICAM1 Recombinant Antibody (clone HumF); Fab Fragment | ELISA, FuncS | Humanized Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-026CQ | Mouse Anti-ICAM1 Recombinant Antibody (clone 8.4A6) | ELISA, FC, Inhib | Mouse IgG1 |
| HPAB-1728-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC1555) | ELISA | Human IgG4 |
| HPAB-1729-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC3040) | ELISA | Human IgG4 |
| HPAB-1730-FY | Human Anti-ICAM1 Recombinant Antibody (clone LAC3041) | ELISA | Human IgG4 |
| HPAB-S0062-YC | Human Anti-ICAM1 Recombinant Antibody (clone HumB) | ELISA, FuncS | Humanized IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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