Human Anti-ICOS Recombinant Antibody (HPAB-0111-CN)
CAT#: HPAB-0111-CN
This product is a recombinant human antibody that recognizes ICOS. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.
Tested Data
Gene Expression
SDS-PAGE
Figure 1 Recombinant Anti-ICOS Antibody (HPAB-0111-CN) in SDS-PAGE
Lane M: Protein Marker
Lane 1: Non-Reducing (2.0ug)
Lane 2: Reducing (2.0ug)
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Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
Subcellular Location
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg
Normal Tissue
Figure 5 Tonsil
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human ICOS
- Species Reactivity
- Human
- Applications
- ELISA, FC, IHC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
Primary Immunodeficiency
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "ICOS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-128CT | Mouse Anti-ICOS Recombinant Antibody (TAB-128CT) | ELISA, WB | Mouse IgG |
| TAB-128CT-S(P) | Mouse Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-128CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-128CT-F(E) | Mouse Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-128CT-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-129CT | Human Anti-ICOS Recombinant Antibody (TAB-129CT) | ELISA, Neut | Human IgG2, κ |
| TAB-129CT-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-129CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-129CT-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-129CT-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2311MZ | Recombinant Mouse Anti-Human ICOS Antibody (clone 26-525), APC-Conjugated | FC | Mouse antibody |
| FN-034CQ | Mouse Anti-ICOS Recombinant Antibody (clone ANC6C6) | ELISA, FC, FuncS | Mouse IgG1, κ |
| FN-184CQ | Hamster Anti-ICOS Recombinant Antibody (clone C398.4A) | FC, FuncS | Hamster IgG |
| HPAB-1261WJ | Human Anti-ICOS Recombinant Antibody (HPAB-1261WJ) | Neut, ELISA | Human IgG |
| HPAB-1262WJ | Human Anti-ICOS Recombinant Antibody (HPAB-1262WJ) | Neut, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-941CQ | Mouse Anti-ICOS Recombinant Antibody (clone CBL817) | Neut, FC, CyTOF | Mouse IgG1 |
| NEUT-942CQ | Rat Anti-Icos Recombinant Antibody (clone 7E.17G9) | FC, FuncS, Neut | Rat IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-943CQ | Rat Anti-Icos Recombinant Antibody (NEUT-943CQ) | Block, FC | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1727 | Rabbit Anti-ICOS Recombinant Antibody (clone DS1727AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0109-CN-S(P) | Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0109-CN-S(P)) | ELISA, FC, IHC | Hamster scFv |
| HPAB-0110-CN-S(P) | Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0110-CN-S(P)) | ELISA, FC, IHC | Hamster scFv |
| HPAB-0073-WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0073-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0022LY-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0022LY-S(P)) | WB | Human scFv |
| HPAB-0052-YJ-S(P) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0109-CN-F(E) | Hamster Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0109-CN-F(E)) | ELISA, FC, IHC | Hamster Fab |
| HPAB-0022LY-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0022LY-F(E)) | WB | Human Fab |
| HPAB-0052-YJ-F(E) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); Fab Fragment | ELISA | Human Fab |
| HPAB-1261WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1261WJ-F(E)) | Neut, ELISA | Human Fab |
| HPAB-1262WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1262WJ-F(E)) | Neut, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1522 | Human Anti-ICOS Recombinant Antibody (clone JTX-2011) | ELISA, FC | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY123 | CytoStream™ Mouse Anti-ICOS Recombinant Antibody (VS-0225-XY123) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY63 | Human Anti-ICOS (clone JMab-136) scFv-Fc Chimera | ELISA, FC | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC522 | Recombinant Anti-ICOS Vesicular Antibody, EV Displayed (VS-0425-YC522) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3374 | Anti-ICOS Immunohistochemistry Kit | IHC |
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