What is the purity of this recombinant antibody?

The purity of this mouse anti-ICOS recombinant antibody is greater than 95% as determined by SDS-PAGE. It is purified using Protein A or G, ensuring a high-quality reagent for your neutralization and cytometry experiments.

Mouse Anti-ICOS Recombinant Antibody (clone CBL817)

CAT#: NEUT-941CQ

This antibody is a mouse monoclonal antibody that binds specifically to ICOS, and it can neutralize the bioactivity of ICOS.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg

Subcellular Location Figure 2 IHC staining of human tonsil

Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg

Normal Tissue Figure 5 Tonsil

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg

RNA Expression Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS

❮

❯

Specifications

Immunogen
Partial Recombinant human ICOS protein

Host Species
Mouse

Type
Mouse IgG1

Specificity
Human ICOS

Species Reactivity
Human

Clone
CBL817

Applications
Neut, FC, CyTOF

Product Property

Purification
Protein A or G purified

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
ICOS; inducible T-cell costimulator; AILIM; CD278; CVID1

Gene ID
29851

UniProt ID
Q9Y6W8

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for NEUT-941CQ. Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Neutralizes ICOS Activity

We chose this antibody for its ability to neutralize the bioactivity of ICOS, and it worked as anticipated. Clone CBL817 is a potent reagent for functional assays involving T-cell costimulator pathways.

Q&As

What is the purity of this recombinant antibody?

A: The purity of this mouse anti-ICOS recombinant antibody is greater than 95% as determined by SDS-PAGE. It is purified using Protein A or G, ensuring a high-quality reagent for your neutralization and cytometry experiments.

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

Primary Immunodeficiency

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - NEUT-941CQ.pdf

MSDS

MSDS - NEUT-941CQ.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "ICOS"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1124z	Mouse Anti-ICOS Recombinant Antibody (clone 41C5)	FC, IHC, IP, FuncS	Mouse IgG1, κ

CAT	Product Name	Application	Type
TAB-128CT	Mouse Anti-ICOS Recombinant Antibody (TAB-128CT)	ELISA, WB	Mouse IgG

CAT	Product Name	Application	Type
TAB-129CT	Human Anti-ICOS Recombinant Antibody (TAB-129CT)	ELISA, Neut	Human IgG2, κ

CAT	Product Name	Application	Type
TAB-128CT-S(P)	Mouse Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-128CT-S(P))	ELISA, WB	Mouse scFv

CAT	Product Name	Application	Type
TAB-129CT-S(P)	Human Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-129CT-S(P))	ELISA, Neut	Human scFv

CAT	Product Name	Application	Type
TAB-128CT-F(E)	Mouse Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-128CT-F(E))	ELISA, WB	Mouse Fab

CAT	Product Name	Application	Type
TAB-129CT-F(E)	Human Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-129CT-F(E))	ELISA, Neut	Human Fab

CAT	Product Name	Application	Type
MOB-2311MZ	Recombinant Mouse Anti-Human ICOS Antibody (clone 26-525), APC-Conjugated	FC	Mouse antibody

CAT	Product Name	Application	Type
NEUT-942CQ	Rat Anti-Icos Recombinant Antibody (clone 7E.17G9)	FC, FuncS, Neut	Rat IgG2b, κ

CAT	Product Name	Application	Type
NEUT-943CQ	Rat Anti-Icos Recombinant Antibody (NEUT-943CQ)	Block, FC	Rat IgG2

CAT	Product Name	Application	Type
MOR-1727	Rabbit Anti-ICOS Recombinant Antibody (clone DS1727AB)	IHC-P	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0109-CN	Hamster Anti-ICOS Recombinant Antibody (HPAB-0109-CN)	ELISA, FC, IHC	Hamster IgG

CAT	Product Name	Application	Type
HPAB-0110-CN	Hamster Anti-ICOS Recombinant Antibody (HPAB-0110-CN)	ELISA, FC, IHC	Hamster IgG

CAT	Product Name	Application	Type
HPAB-0111-CN	Human Anti-ICOS Recombinant Antibody (HPAB-0111-CN)	ELISA, FC, IHC	Humanized IgG

CAT	Product Name	Application	Type
HPAB-0109-CN-S(P)	Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0109-CN-S(P))	ELISA, FC, IHC	Hamster scFv

CAT	Product Name	Application	Type
HPAB-0110-CN-S(P)	Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0110-CN-S(P))	ELISA, FC, IHC	Hamster scFv

CAT	Product Name	Application	Type
HPAB-0111-CN-S(P)	Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0111-CN-S(P))	ELISA, FC, IHC	Humanized scFv

CAT	Product Name	Application	Type
HPAB-0109-CN-F(E)	Hamster Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0109-CN-F(E))	ELISA, FC, IHC	Hamster Fab

CAT	Product Name	Application	Type
HPAB-0110-CN-F(E)	Hamster Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0110-CN-F(E))	ELISA, FC, IHC	Hamster Fab

CAT	Product Name	Application	Type
HPAB-0111-CN-F(E)	Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0111-CN-F(E))	ELISA, FC, IHC	Humanized Fab

CAT	Product Name	Application	Type
HPAB-0073-WJ-S(P)	Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0073-WJ-S(P))	ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-0073-WJ-F(E)	Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0073-WJ-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
HPAB-0022LY-S(P)	Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0022LY-S(P))	WB	Human scFv

CAT	Product Name	Application	Type
HPAB-0022LY-F(E)	Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0022LY-F(E))	WB	Human Fab

CAT	Product Name	Application	Type
VS3-WK1522	Human Anti-ICOS Recombinant Antibody (clone JTX-2011)	ELISA, FC	Humanized IgG1

CAT	Product Name	Application	Type
VS-0225-XY123	CytoStream™ Mouse Anti-ICOS Recombinant Antibody (VS-0225-XY123)	FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0425-FY63	Human Anti-ICOS (clone JMab-136) scFv-Fc Chimera	ELISA, FC	Human IgG2, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC522	Recombinant Anti-ICOS Vesicular Antibody, EV Displayed (VS-0425-YC522)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY3374	Anti-ICOS Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0825-YC160	SmartAb™ Recombinant Anti-ICOS pH-dependent Antibody (VS-0825-YC160)	ELISA	Human IgG2 kappa

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 3 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in ELISA

Anti-Human NRP1 Recombinant Antibody (Vesencumab) (CAT# TAB-264)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 2 Anti-SLAMF7 Recombinant Antibody (TAB-743) in WB

Anti-SLAMF7 Recombinant Antibody (Elotuzumab) (CAT# TAB-743)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 9 Anti-Human BAFF Recombinant Antibody in ELISA

Anti-Human BAFF Recombinant Antibody (TAB-216) (CAT# TAB-216)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 1 Human TWEAK receptor Therapeutic Antibody (TAB-178) in ELISA

Anti-Human TWEAK receptor Recombinant Antibody (TAB-178) (CAT# TAB-178)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 6 Anti-Human VEGF Recombinant Antibody (TAB-011) in ELISA

Anti-Human VEGF Recombinant Antibody (Bevacizumab) (CAT# TAB-011)
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC

Figure 2 Anti-Human CD83 Recombinant Antibody (TAB-143CL) in HPLC

Anti-Human CD83 Recombinant Antibody (CAT# TAB-143CL)
Application:

Figure 2 Recombinant Mouse Anti-uPAR Antibody (PABL-355) in ELISA

Mouse Anti-PLAUR Recombinant Antibody (PABL-355) (CAT# PABL-355)
Application: WB, ELISA, FuncS

Figure 6 Anti-LAM Recombinant Antibody (PABW-158, lot#CB2206LX02P6) in SEC-HPLC

Mouse Anti-LAM Recombinant Antibody (clone CS-35) (CAT# PABW-158)
Application: ELISA, IF, FC

Figure 3 Anti-Human IgE Antibody (TAB-095ZJ) in ELISA

Anti-Human IgE Single Domain Antibody (TAB-095ZJ), Research Grade Biosimilar (CAT# TAB-095ZJ)
Application: ELISA, Inhib, FC

Figure 1 Anti-Human RNF43 Recombinant Antibody (TAB-327CT) in SDS-PAGE

Mouse Anti-RNF43 Recombinant Antibody (TAB-327CT) (CAT# TAB-327CT)
Application: WB, ELISA, FC, IHC, IP

Figure 2 Anti-Human TEM7R Recombinant Antibody (TAB-577CT) in HPLC

Human Anti-PLXDC2 Recombinant Antibody (TAB-577CT) (CAT# TAB-577CT)
Application: ELISA, FC, IHC, IF

Figure 2 Anti-Human RNF43 Recombinant Antibody scFv Fragment (TAB-328CT-S(P)) in HPLC

Humanized Anti-RNF43 Recombinant Antibody; scFv Fragment (TAB-328CT-S(P)) (CAT# TAB-328CT-S(P))
Application: WB, ELISA, FC, IHC, IP

Figure 3 Anti-Human SLC1A5 Recombinant Antibody (TAB-1009CLV) in FC

Anti-Human SLC1A5 Recombinant Antibody (TAB-1009CLV) (CAT# TAB-1009CLV)
Application: FC, ADCC, CDC, Inhib

Figure 3 Anti-CD27 Recombinant Antibody (MOB-096LC) in DB

Human Anti-CD27 Recombinant Antibody (MOB-096LC) (CAT# MOB-096LC)
Application: ELISA, FuncS, WB

Figure 1 Human IgG2, kappa Isotype Control Antibody (MOB-197CQ) in SDS-PAGE

Human IgG2, kappa Isotype Control Antibody (CAT# MOB-197CQ)
Application: FC, ELISA

Figure 4 Mouse Anti-EGFR Recombinant Antibody (HPAB-0727-CN) in WB

Mouse Anti-EGFR Recombinant Antibody (clone EGFR) (CAT# HPAB-0727-CN)
Application: ELISA, FC, IHC, Neut

Figure 4 Mouse Anti-PSCA Recombinant Antibody (HPAB-0287CQ) in WB

Mouse Anti-PSCA Recombinant Antibody (clone mAb 8D11) (CAT# HPAB-0287CQ)
Application: FC, IHC, Cyt, FuncS

Figure 2 Human Anti-EBV gB Recombinant Antibody (Clone AMMO4) (PABS-0039) in WB

Human Anti-EBV gB Recombinant Antibody (Clone AMMO4) (CAT# PABS-0039)
Application: ELISA, FuncS

Figure 3 Human Anti-HLA-A*11:01 Recombinant Antibody, APC (PABJ-0146-APC) in full-wavelength scanning analysis.

Human Anti-HLA-A*11:01 Recombinant Antibody (clone 2E3) (CAT# PABJ-0146)
Application: ELISA, FC, FuncS

Figure 3 Mouse Anti-E-Tag Antibody (ZG-0287U) in ELISA

Mouse Anti-E-Tag Recombinant Antibody (clone 11H12B3) (CAT# ZG-0287U)
Application: ELISA, WB, IP

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.