Anti-IFNAR Recombinant Antibody (Anifrolumab) (CAT#: TAB-722)

Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.

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SDS-PAGE

Figure 1 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in SDS-PAGE

Figure 1 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in SDS-PAGE

SDS-PAGE analysis of TAB-722 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.

The purity of TAB-722 was greater than 95% as determined by SDS-PAGE.

SEC-HPLC

Figure 2 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in HPLC

Figure 2 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in HPLC

The purity of TAB-722 was greater than 95% as determined by SEC-HPLC.

ELISA

Figure 3 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in ELISA

Figure 3 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in ELISA

ELISA analysis of TAB-722 was performed by coating with human IFNAR1 protein (His Tag).

The secondary antibody: HRP-anti-human IgG


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods.
  • CAS
  • 1326232-46-5
  • Generic Name
  • anifrolumab
  • MW
  • 145.12 kDa
  • Related Disease
  • Diffuse scleroderma

Product Property

  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • anifrolumab;1326232-46-5;MEDI-546;interferon-α/β receptor;IFNAR

Related Resources

  • Biosimilar Overview
  • Citations
Please refer to Anifrolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Anifrolumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Anifrolumab"

Afuco™ Anti-IFNAR ADCC Recombinant Antibody (Anifrolumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.

See other products for "IFNAR"

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Single-domain Antibody
CAT Product Name Application Type
NAB-1570-VHH Recombinant Anti-Human IFNAR VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

Customer Reviews and Q&As

Customer Review Q&As

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  • Ideal for IFNAR Research
    The Anti-IFNAR Therapeutic Antibody (anifrolumab) has been excellent for our IFNAR studies. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
  • Reliable in Multiple Assays
    We incorporated this antibody into our Western blot and immunoassays, and it has been a great asset. The specificity for IFNAR is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
  • Consistent High-Quality Results
    This antibody has proven to be consistent and high-quality in our various assays. The reproducible results and strong affinity for IFNAR have significantly improved our experiments, making it a crucial part of our research toolkit. The consistent performance has greatly enhanced our data quality.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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