Human Anti-IFNAR1 Recombinant Antibody (clone S3A5) (CAT#: HPAB-0158-CN)

Antibody S3A5 is a novel human antibody that specifically binds to human IFNAR1, which can inhibit the type I interferon-mediated cell signaling pathway.


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  • Published Data
  • Gene Expression
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FC

Figure 1 IFNAR blockade during cART-suppressed HIV-1 infection reverses the exhaustion phenotype of CD8 T cells and restores anti–HIV-1 T cell function.

Figure 1 IFNAR blockade during cART-suppressed HIV-1 infection reverses the exhaustion phenotype of CD8 T cells and restores anti–HIV-1 T cell function.

Splenocytes were stimulated ex vivo with HIV-1 Gag peptide pools for 8 hours.

Cheng, L., Ma, J., Li, J., Li, D., Li, G., Li, F., ... & Tsao, L. C. (2017). Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. The Journal of clinical investigation, 127(1), 269-279.


Specifications

  • Immunogen
  • Recombinant hIFNARl-his
  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human IFNAR1
  • Species Reactivity
  • Human
  • Clone
  • S3A5
  • Applications
  • FC
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The IFNAR1 antibody has been reported in applications of Flow Cytometry.

Target

  • Alternative Names
  • AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone S3A5"

See other products for "IFNAR1"

Humanized Antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-976CQ Mouse Anti-Ifnar1 Recombinant Antibody (clone MAR1-5A3) FC, Neut, IP, WB, B Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1740 Rabbit Anti-IFNAR1 Recombinant Antibody (clone DS1740AB) WB, FC, IP Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
MOB-161CQ Goat Anti-Human IFNAR1 Polyclonal Antibody ELISA, FC, Neut, WB Goat IgG
HPAB-0203CQ Human Anti-IFNAR1 Recombinant Antibody (clone H3K1) ELISA, FC, Inhib Humanized IgG1
HPAB-0204CQ Human Anti-IFNAR1 Recombinant Antibody (HPAB-0204CQ) ELISA, WB, FC, Inhib, FuncS Human IgG1
HPAB-0205CQ Human Anti-IFNAR1 Recombinant Antibody (HPAB-0205CQ) ELISA, WB, FC, Inhib Human IgG1
HPAB-0206CQ Human Anti-IFNAR1 Recombinant Antibody (HPAB-0206CQ) ELISA, WB, FC, Inhib Human IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-722 Afuco™ Anti-IFNAR ADCC Recombinant Antibody (Anifrolumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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