Mouse Anti-IFNGR1 Recombinant Antibody (clone A6); Fab Fragment (CAT#: PFBC-080)
Recombinant Mouse Antibody (A6) Fab Fragment is specific to IFNGR1, expressed in Chinese Hamster Ovary cells (CHO). The epitope on the IFNγR(1-108) domain recognized by A6 largely overlaps the contiguous surface that is recognized by IFNγ.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29213/273_A10_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29213/273_A10_2_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong membranous positivity in cells in red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_9_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong membranous positivity in cells in red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_9_4_selected.jpg
Figure 3 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25889/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25889/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_8_5.jpg
Figure 5 Lung
(Macrophages Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_A_1_4.jpg
(Macrophages Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_A_1_4.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000027697-IFNGR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000027697-IFNGR1
Specifications
- Immunogen
- Human interferon gamma receptor 1
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human IFNGR1
- Species Reactivity
- Human
- Clone
- A6
- Applications
- Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IFNGR1; interferon gamma receptor 1; CD119; IFNGR; IMD27A; IMD27B; CDw119; AVP, type 2; IFN-gamma-R1; CD119 antigen; IFN-gamma receptor 1; antiviral protein, type 2; immune interferon receptor 1; interferon-gamma receptor alpha chain;
- Gene ID
- 3459
- UniProt ID
- P15260
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone A6"
See other products for "IFNGR1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1758z | Mouse Anti-IFNGR1 Recombinant Antibody (clone 22B6) | WB, ELISA, FC, IHC | Mouse IgG2a |
| MOB-2323MZ | Recombinant Mouse Anti-Human IFNGR1 Antibody (clone NN0440-0V20) | FC, Neut, WB | Mouse antibody |
| FAMAB-0193CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38) | ELISA, RIA | Mouse IgG |
| FAMAB-0194CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99) | ELISA, RIA | Mouse IgG |
| FAMAB-1381CQ | Rabbit Anti-IFNGR1 Recombinant Antibody (clone GR20) | Block, Neut, FC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-080 | Mouse Anti-IFNGR1 Recombinant Antibody (clone A6); scFv Fragment | Neut | Mouse scFv |
| FAMAB-0193CQ-S(P) | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38); scFv Fragment | ELISA, RIA | Mouse scFv |
| FAMAB-0194CQ-S(P) | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99); scFv Fragment | ELISA, RIA | Mouse scFv |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1038CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone GIR 208) | FC, IP, Block, IHC, WB | Mouse IgG1, κ |
| NEUT-1043CQ | Rat Anti-Ifngr1 Recombinant Antibody (clone mAb0830) | Block, FC | Rat IgG2 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1039CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone CBL509) | WB, FC, CyTOF, Neut | Mouse IgG1 |
| NEUT-1040CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone MM0339-9U19) | WB, Neut, FC | Mouse IgG1 |
| NEUT-1041CQ | Rat Anti-Ifngr1 Recombinant Antibody (clone GR-20) | FC, FuncS, Neut | Rat IgG2a, κ |
| NEUT-1042CQ | Rat Anti-Ifngr1 Recombinant Antibody (clone CBL577) | ELISA, Neut | Rat IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1743 | Rabbit Anti-IFNGR1 Recombinant Antibody (clone DS1743AB) | WB, IHC, ICC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0193CQ-F(E) | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38); Fab Fragment | ELISA, RIA | Mouse Fab |
| FAMAB-0194CQ-F(E) | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99); Fab Fragment | ELISA, RIA | Mouse Fab |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0893 | PE-H-2Kb/IFNGR1 (TSYKFESV) MHC Tetramer | FCM, IHC | |
| MHC-CN0894 | APC-H-2Kb/IFNGR1 (TSYKFESV) MHC Tetramer | FCM, IHC | |
| MHC-CN0895 | FITC-H-2Kb/IFNGR1 (TSYKFESV) MHC Tetramer | FCM, IHC | |
| MHC-CN0896 | H-2Kb/IFNGR1 (TSYKFESV) MHC Tetramer | FCM, IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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