Anti-Human IL-1R (Interleukin 1) Recombinant Antibody (ch2D8)
CAT#: TAB-219CT
Recombinant monoclonal antibody to interleukin 1 receptor type 1. ch2D8 is a chimeric(rat/human) antibody intended for the prophylaxis and treatment of inflammatory disease.
Specifications
- Host Species
- Human
- Type
- Chimeric antibody (rat/human)
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- ch2D8
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization; Blocking; Western Blot; Inhibition
- Related Disease
- Inflammatory disease
Target
- Alternative Names
- This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
- Gene ID
- 3554
- UniProt ID
- P14778
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TAB-219CT. Click the button above to contact us or submit your feedback about this product.
Effective Blocking Antibody
We used the ch2D8 clone for blocking assays involving the interleukin 1 receptor type 1. It functioned effectively as an inhibitor in our system. The chimeric nature of the antibody makes it an interesting tool for our specific research needs.
Verified Neutralization Capability
This antibody was tested for neutralization of IL-1R signaling in our cell-based assays. It showed clear inhibitory effects. We also confirmed its binding via ELISA, where it performed with high sensitivity and reproducibility.
Q&As
-
Is this a chimeric antibody?
A: Yes, this is a chimeric (rat/human) recombinant monoclonal antibody. The clone ch2D8 is designed to bind to interleukin 1 receptor type 1 and is intended for research into the prophylaxis and treatment of inflammatory disease.
-
What functional applications is this antibody suitable for?
A: This antibody is suitable for Neutralization, Blocking, and Inhibition assays. It can also be used in Enzyme-linked Immunosorbent Assay (ELISA) and Western Blot (WB) to study the interaction of IL-1R with its ligands.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone ch2D8"
- CAT
- Product Name
See other products for "IL1R"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218CT | Anti-Human IL-1R (Interleukin 1) Recombinant Antibody (2D8) | ELISA, Neut, BL, WB, Inhibition |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218CT-S(P) | Anti-Human IL-1R (Interleukin 1) Recombinant Antibody scFv Fragment (2D8) | ELISA, Neut, BL, WB, Inhibition |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219CT-S(P) | Anti-Human IL-1R (Interleukin 1) Recombinant Antibody scFv Fragment (ch2D8) | ELISA, Neut, BL, WB, Inhibition | Chimeric antibody (rat/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218CT-F(E) | Anti-Human IL-1R (Interleukin 1) Recombinant Antibody Fab Fragment (2D8) | ELISA, Neut, BL, WB, Inhibition |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219CT-F(E) | Anti-Human IL-1R (Interleukin 1) Recombinant Antibody Fab Fragment (ch2D8) | ELISA, Neut, BL, WB, Inhibition | Chimeric antibody (rat/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-107LC | Recombinant Anti-Human IL-1R Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0154MZ | Recombinant Mouse Anti-IL-1 Receptor Antibody (clone CDI205) | ELISA, RIA, IHC | Mouse antibody |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: Neut, ELISA, Inhib, ICC, WB
-5.jpg)
Application: ELISA, Neut
Application: ELISA, Neut
Application: FC, IA, IF, IP, IHC, FuncS
Application: ELISA, FC, WB, Inhib, IHC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
