Recombinant Human Antibody (CNTO607) is capable of binding to IL13, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL13 mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti- IL13 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. CNTO607 binds human IL-13 with high affinity (Kd=15 pM) and prevents binding of IL-13 to both IL-13Rα1 and IL- 13Rα2. CNTO607 potently neutralizes the activity of IL-13 in a variety of bioassays, including cell survival, eotaxin production, and STAT6 signaling.
Figure 1 Anti-IL13 Recombinant Antibody (PABW-170) in ELISA
ELISA analysis of PABW-170 was performed by coating with human IL13 protein (His tag). Then blocked with BSA and incubated with PABW-170. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Figure 2 Anti-IL13 Recombinant Antibody (PABW-170) in WB
Western blot analysis of PABW-170 was performed by loading human IL13 protein (Lane 1 0.6 μg) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with PABW-170 and a HRP goat anti-human IgG (H+L) was used as the secondary antibody (1: 3000). Chemiluminescent detection was performed.
Figure 3 Anti-IL13 Recombinant Antibody (PABW-170) in DB
Dot Blot analysis of PABW-170 was performed by coating with human IL13 protein (His tag).
PABW-170 incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG (H+L) secondary antibody (1: 3000)
NC: Negative control, PC: Positive control
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-219 | Anti-Human IL13 Recombinant Antibody (Lebrikizumab) | ELISA, Neut, IF, IP, FC, FuncS | IgG4 - kappa |
TAB-043ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (Lc6Hc2) | ELISA | Humanized antibody |
TAB-044ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-044ZJ-S(P)) | ELISA, Neut | Humanized scFv |
TAB-045ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-045ZJ-S(P)) | ELISA, Block | Humanized scFv |
TAB-046ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-046ZJ-S(P)) | ELISA, Block | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295) | WB, IHC, FuncS | Human IgG |
HPAB-0226CQ | Human Anti-IL13 Recombinant Antibody (HPAB-0226CQ) | ELISA, Neut, FC, FuncS | Human IgG2 |
HPAB-0227CQ | Human Anti-IL13 Recombinant Antibody (HPAB-0227CQ) | ELISA, Neut, FC, FuncS | Human IgG2 |
HPAB-0228CQ | Mouse Anti-IL13 Recombinant Antibody (clone MJ2-7) | ELISA, FC, Neut, FuncS | Mouse IgG |
HPAB-0229CQ | Human Anti-IL13 Recombinant Antibody (clone huMJ2-7) | ELISA, FC, DB, Neut, FuncS | Humanized IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-598 | Mouse Anti-IL13 Recombinant Antibody (clone C836); scFv Fragment | Neut | Mouse scFv |
PSBL-600 | Human Anti-IL13 Recombinant Antibody (clone H2L6); scFv Fragment | ELISA | Humanized scFv |
PSBL-601 | Mouse Anti-IL13 Recombinant Antibody (clone X836); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
HPAB-0226CQ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0226CQ-S(P)) | ELISA, Neut, FC, FuncS | Human scFv |
HPAB-0227CQ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-0227CQ-S(P)) | ELISA, Neut, FC, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-022ZJ | Anti-Human IL-13 Recombinant Antibody (C836) | ELISA | |
TAB-023ZJ | Mouse Anti-IL13 Recombinant Antibody (TAB-023ZJ) | ELISA, Block | Mouse IgG |
TAB-022ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (C836) | ELISA | |
TAB-023ZJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-023ZJ-S(P)) | ELISA, Block | Mouse scFv |
TAB-022ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (C836) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-094ZJ | Anti-Human IL-13 Recombinant Antibody (167) | ELISA | Chimeric antibody (mouse/human) |
TAB-094ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
TAB-094ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-067ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (CNTO 607) | ELISA, Inhib | Human antibody |
TAB-068ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (01471/G6) | ELISA, Neut | Human antibody |
TAB-069ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-069ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
TAB-070ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-070ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
PABX-115-S (P) | Recombinant Human Anti-IL-13 Antibody scFv Fragment (C836) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1171CQ | Mouse Anti-IL13 Recombinant Antibody (clone B-B13) | ELISA, ELISPOT, Neut | Mouse IgG1 |
NEUT-1172CQ | Mouse Anti-IL13 Recombinant Antibody (clone 10X28) | Neut, WB | Mouse IgG1 |
NEUT-1173CQ | Mouse Anti-IL13 Recombinant Antibody (clone 15H10) | Neut | Mouse IgG2b |
NEUT-1174CQ | Mouse Anti-IL13 Recombinant Antibody (clone 32116.11) | ELISA, Neut, WB | Mouse IgG1 |
NEUT-1175CQ | Rat Anti-IL13 Recombinant Antibody (clone 5A2) | Neut | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1790 | Rabbit Anti-IL13 Recombinant Antibody (clone DS1790AB) | WB, ICC, FC, IP | Rabbit IgG |
MOR-4610 | Rabbit Anti-IL13 Recombinant Antibody (clone TH123DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H05 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-017ML | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
AFC-TAB-219 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
AFC-TAB-218 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0355-WJ-F(E) | Human Anti-IL13 Recombinant Antibody (clone 13C5.5); Fab Fragment | ELISA | Humanized Fab |
HPAB-1739-FY-S(P) | Mouse Anti-IL13 Recombinant Antibody (clone mAb13.2); Fab Fragment | Inhib, ELISA | Mouse Fab |
HPAB-1740-FY-S(P) | Human Anti-IL13 Recombinant Antibody (clone ch13.2); Fab Fragment | Inhib, ELISA | Chimeric (mouse/human) Fab |
HPAB-1741-FY-S(P) | Human Anti-IL13 Recombinant Antibody (clone h13.2v1); Fab Fragment | Inhib, ELISA | Humanized Fab |
HPAB-1742-FY-S(P) | Human Anti-IL13 Recombinant Antibody (clone V2.11); Fab Fragment | ELISA, Inhib | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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