Human Anti-IL17A Recombinant Antibody (clone B5) (CAT#: HPAB-0217-LSX)
Recombinant monoclonal antibody to IL17A. Clone B5 is a human monoclonal antibody that can be potentially used in the treatment of inflammatory, cancer, allergic diseases and autoimmune diseases.
Specific Inquiry
IHC
Figure 1 IL-17A expression is localized to the inflamed joint.
Immunohistochemistry was performed in synovial tissue sections from patients with inflammatory arthritis (n = 19).
Moran, E. M., Heydrich, R., Ng, C. T., Saber, T. P., McCormick, J., Sieper, J., ... & Veale, D. J. (2011). IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates. PloS one, 6(8), e24048.
IF
Figure 2 Localisation of IL-17A to neutrophils and mast cells within the inflamed synovium.
Representative images of RA synovial tissue section stained with antibodies against IL-17A.
Moran, E. M., Heydrich, R., Ng, C. T., Saber, T. P., McCormick, J., Sieper, J., ... & Veale, D. J. (2011). IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates. PloS one, 6(8), e24048.
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human IL17A
- Species Reactivity
- Human, Cynomolgus
- Clone
- B5
- Applications
- IF, IHC
- Related Disease
- Inflammation, cancer, allergic diseases and autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL17A antibody has been reported in applications of Immunofluorescence, Immunohistochemistry.
Target
Related Resources
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H08 | Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-048ZJ | Human Anti-IL17A Recombinant Antibody (TAB-048ZJ) | ELISA, Neut | Humanized antibody |
| TAB-048ZJ-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-048ZJ-S(P)) | ELISA, Neut | Human scFv |
| TAB-048ZJ-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-048ZJ-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-458CQ | Anti-Human IL17A Recombinant Antibody (TAB-458CQ) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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