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  • Human Anti-IL18 Recombinant Antibody (clone YC127); Fab Fragment

Human Anti-IL18 Recombinant Antibody (clone YC127); Fab Fragment (CAT#: PFBL-602)

Recombinant Human Antibody Fab Fragment is specific to IL18, expressed in Chinese Hamster Ovary cells (CHO).


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  • Gene Expression
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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3980/16_G12_1_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3980/14_G12_1_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3980/13_G12_1_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7772/19579_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7772/19579_A_8_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Collecting ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7772/19579_A_9_5.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7772/19579_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, PC-3, U-2 OS)
Figure 8 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, PC-3, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150782-IL18
Figure 8 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, PC-3, U-2 OS)
Figure 8 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, PC-3, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150782-IL18

Specifications

  • Immunogen
  • Human interleukin 18
  • Host Species
  • Human
  • Type
  • Human Fab
  • Specificity
  • Human IL18
  • Species Reactivity
  • Human
  • Clone
  • YC127
  • Applications
  • WB, ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • IL18; interleukin 18; IGIF; IL-18; IL-1g; IL1F4; interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor)

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone YC127"

See other products for "IL18"

scFv Fragment Antibody

CAT Product Name Application Type
PSBW-081 Mouse Anti-IL18 Recombinant Antibody (clone 125-2H); scFv Fragment ELISA, Neut Mouse scFv
PSBL-602 Human Anti-IL18 Recombinant Antibody (clone YC127); scFv Fragment WB, ELISA, FuncS Human scFv
HPAB-0065-YC-S(P) Human Anti-IL18 Recombinant Antibody (clone LT28); scFv Fragment ELISA, RIA, IHC, FuncS, Neut Human scFv
HPAB-0062-YJ-S(P) Mouse Anti-IL18 Recombinant Antibody (clone 13G9); scFv Fragment IA, Neut Mouse scFv
HPAB-J0129-YC-S(P) Human Anti-IL18 Recombinant Antibody (clone ABT-325); scFv Fragment ELISA Human scFv

Human Antibody

CAT Product Name Application Type
TAB-0373CL Human Anti-IL18 Recombinant Antibody (TAB-0373CL) ELISA, FuncS, Inhib Human IgG
TAB-0374CL Human Anti-IL18 Recombinant Antibody (TAB-0374CL) ELISA, FuncS, Inhib Human IgG
TAB-0373CL-S(P) Human Anti-IL18 Recombinant Antibody; scFv Fragment (TAB-0373CL-S(P)) ELISA, FuncS, Inhib Human scFv
TAB-0374CL-S(P) Human Anti-IL18 Recombinant Antibody; scFv Fragment (TAB-0374CL-S(P)) ELISA, FuncS, Inhib Human scFv
TAB-0373CL-F(E) Human Anti-IL18 Recombinant Antibody; Fab Fragment (TAB-0373CL-F(E)) ELISA, FuncS, Inhib Human Fab

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0290MZ Chicken Anti-Interleukin-18 Polyclonal IgY Indirect ELISA, WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1238CQ Rabbit Anti-IL18 Recombinant Antibody (clone 1072F) Neut Rabbit IgG
NEUT-1239CQ Rat Anti-Il18 Recombinant Antibody (clone 39-3F) Neut, WB Rat IgG2a
NEUT-1240CQ Mouse Anti-IL18 Recombinant Antibody (clone CBL670) Neut Mouse IgG2a
NEUT-1241CQ Rat Anti-Il18 Recombinant Antibody (clone YIGIF74-1G7) Neut Rat IgG2a
NEUT-1242CQ Rat Anti-Il18 Recombinant Antibody (clone 93-10C) IP, Neut Rat IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4248 Rabbit Anti-IL18 Recombinant Antibody (clone SI327DS) ELISA Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0066-YC Human Anti-IL18 Recombinant Antibody (HPAB-0066-YC) Neut Humanized IgG2
HPAB-0067-YC Rat Anti-IL18 Recombinant Antibody (clone 2C10) Neut Rat IgG
HPAB-0065-YC Human Anti-IL18 Recombinant Antibody (clone LT28) ELISA, RIA, IHC, FuncS, Neut Human IgG
HPAB-0062-YJ Mouse Anti-IL18 Recombinant Antibody (clone 13G9) Inhib, FC, IHC, ELISA Mouse IgG1, κ
HPAB-0064-YJ Rat Anti-IL18 Recombinant Antibody (clone 14B7) IF, FC, IHC, WB Rat IgG1, κ

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-1273LY-F(E) Human Anti-IL18 Recombinant Antibody; Fab Fragment (HPAB-1273LY-F(E)) ELISA, Inhib Human Fab
HPAB-0855-FY-S(P) Human Anti-IL18 Recombinant Antibody (clone 2.5); Fab Fragment ELISA Human Fab
HPAB-0856-FY-S(P) Human Anti-IL18 Recombinant Antibody; scFv Fragment (HPAB-0856-FY-S(P)) Inhib Human scFv
HPAB-0857-FY-S(P) Human Anti-IL18 Recombinant Antibody; scFv Fragment (HPAB-0857-FY-S(P)) Inhib Human scFv
HPAB-0092-WJ-F(E) Human Anti-IL18 Recombinant Antibody (clone 2.5(E)); Fab Fragment ELISA Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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