Interleukin-18 (IL-18) is a potent cytokine that plays a role in both innate and acquired immune responses. IL-18 was first identified for its ability to induce the production of IFN-ɣ, one of the primary effector molecules of a T helper (Th) 1-type immune response. Anti-IL-18 antibodies may be useful for example, in diagnosing and treating disorders associated with elevated IL-18 levels, including inflammatory, cardiovascular and autoimmune diseases
Figure 1 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in DB
Dot Blot analysis of HPAB-0067-YC-S(P) was performed by coating with human IL18 protein (His tag).
HPAB-0067-YC-S(P) incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-His tag as a secondary antibody (1: 2000)
Figure 2 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in WB
Western blot analysis of HPAB-0067-YC-S(P) was performed by loading human IL18 protein (Lane 1 0.1 μg, Lane 2 0.3 μg, Lane 3 0.6 μg) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with HPAB-0067-YC-S(P) and HRP goat anti-His tag as a secondary antibody (1: 2000). Chemiluminescent detection was performed.
Figure 3 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in ELISA
ELISA analysis of HPAB-0067-YC-S(P) was performed by coating with human IL18 protein (His tag). Then blocked with BSA and incubated with HPAB-0067-YC-S(P). The HRP-conjugated goat anti-His tag as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
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• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1332z | Mouse Anti-IL18 Recombinant Antibody (clone 27G4) | WB, IF, ELISA | Mouse IgG2b |
PABL-607 | Human Anti-IL18 Recombinant Antibody (clone YC126) | WB, ELISA, FuncS | Human IgG |
FN-113CQ | Mouse Anti-IL18 Recombinant Antibody (clone 125-2H) | IP, Neut | Mouse IgG1, κ |
HPAB-0062-YJ | Mouse Anti-IL18 Recombinant Antibody (clone 13G9) | Inhib, FC, IHC, ELISA | Mouse IgG1, κ |
HPAB-0064-YJ | Rat Anti-IL18 Recombinant Antibody (clone 14B7) | IF, FC, IHC, WB | Rat IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0373CL | Human Anti-IL18 Recombinant Antibody (TAB-0373CL) | ELISA, FuncS, Inhib | Human IgG |
TAB-0374CL | Human Anti-IL18 Recombinant Antibody (TAB-0374CL) | ELISA, FuncS, Inhib | Human IgG |
TAB-0373CL-S(P) | Human Anti-IL18 Recombinant Antibody; scFv Fragment (TAB-0373CL-S(P)) | ELISA, FuncS, Inhib | Human scFv |
TAB-0373CL-F(E) | Human Anti-IL18 Recombinant Antibody; Fab Fragment (TAB-0373CL-F(E)) | ELISA, FuncS, Inhib | Human Fab |
TAB-0374CL-F(E) | Human Anti-IL18 Recombinant Antibody; Fab Fragment (TAB-0374CL-F(E)) | ELISA, FuncS, Inhib | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0290MZ | Chicken Anti-Interleukin-18 Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1238CQ | Rabbit Anti-IL18 Recombinant Antibody (clone 1072F) | Neut | Rabbit IgG |
NEUT-1239CQ | Rat Anti-Il18 Recombinant Antibody (clone 39-3F) | Neut, WB | Rat IgG2a |
NEUT-1240CQ | Mouse Anti-IL18 Recombinant Antibody (clone CBL670) | Neut | Mouse IgG2a |
NEUT-1241CQ | Rat Anti-Il18 Recombinant Antibody (clone YIGIF74-1G7) | Neut | Rat IgG2a |
NEUT-1242CQ | Rat Anti-Il18 Recombinant Antibody (clone 93-10C) | IP, Neut | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4248 | Rabbit Anti-IL18 Recombinant Antibody (clone SI327DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0065-YC-F(E) | Human Anti-IL18 Recombinant Antibody (clone LT28); Fab Fragment | ELISA, RIA, IHC, FuncS, Neut | Human Fab |
FAMAB-0229-CN-F(E) | Human Anti-IL18 Recombinant Antibody (clone 1I1G); Fab Fragment | WB, ELISA | Human Fab |
FAMAB-0230-CN-F(E) | Human Anti-IL18 Recombinant Antibody (clone 3I1E); Fab Fragment | WB, ELISA | Human Fab |
FAMAB-0231-CN-F(E) | Human Anti-IL18 Recombinant Antibody (clone 4I3E); Fab Fragment | WB, ELISA | Human Fab |
FAMAB-0232-CN-F(E) | Human Anti-IL18 Recombinant Antibody (clone 5I4E); Fab Fragment | WB, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0649-CN-S(P) | Human Anti-IL18 Recombinant Antibody; scFv Fragment (HPAB-0649-CN-S(P)) | ELISA, Neut | Humanized scFv |
HPAB-0650-CN-S(P) | Rat Anti-IL18 Recombinant Antibody; scFv Fragment (HPAB-0650-CN-S(P)) | ELISA, Neut | Rat scFv |
HPAB-0855-FY-F(E) | Human Anti-IL18 Recombinant Antibody (clone 2.5); scFv Fragment | ELISA | Human scFv |
HPAB-0856-FY-F(E) | Human Anti-IL18 Recombinant Antibody; Fab Fragment (HPAB-0856-FY-F(E)) | Inhib | Human Fab |
FAMAB-0041JF-S(P) | Human Anti-IL18 Recombinant Antibody (clone h18-108); scFv Fragment | IB, FC, ELISA, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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